1. 重组蛋白
  2. Immune Checkpoint Proteins CD Antigens
  3. Stimulatory Immune Checkpoint Molecules NK Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins
  4. 2B4/CD244
  5. 2B4/CD244 蛋白, Human (200a.a, HEK293, His)

2B4/CD244 蛋白, Human (200a.a, HEK293, His)

目录号: HY-P72745
产品使用指南

2B4/CD244 蛋白与 CD48 的结合表现出更高的亲和力,超过同工型 1,导致细胞毒性和细胞内钙释放增加。更强的相互作用意味着更强有力的参与,可能放大细胞反应,特别是增强细胞毒性活性和细胞内钙释放。2B4/CD244 蛋白, Human (200a.a, HEK293, His) 是重组的 2B4/CD244 蛋白,由 HEK293 表达,带有 C-6*His 标签。2B4/CD244 蛋白, Human (200a.a, HEK293, His) 全长 200 个氨基酸,分子量为 35-60 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

2B4/CD244 protein exhibits heightened affinity for binding to CD48, surpassing isoform 1, leading to increased cytotoxicity and intracellular calcium release. The stronger interaction implies more robust engagement, potentially amplifying cellular responses, particularly heightened cytotoxic activity and intracellular calcium release. 2B4/CD244 Protein, Human (200a.a, HEK293, His) is the recombinant human-derived 2B4/CD244 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of 2B4/CD244 Protein, Human (200a.a, HEK293, His) is 200 a.a., with molecular weight of 35-60 kDa.

研究背景

与异构体 1 相比,2B4/CD244 蛋白与 CD48 结合的亲和力更高,这种相互作用导致细胞毒性和细胞内钙释放增强。2B4/CD244CD48 之间更强的结合表明更牢固的结合,可能导致增强的细胞反应,包括增加细胞毒活性和细胞内钙的释放。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q9BZW8-2 (C22-R221)

基因 ID
蛋白结构
N-term
CD244 (C22-R221)
Accession # Q9BZW8-2
6*His
C-term
同用名
Natural killer cell receptor 2B4; NAIL; NKR2B4; h2B4; SLAMF4; CD244; 2B4
氨基酸序列

CQGSADHVVSISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNLSLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVALSCLVSRDGNVSYAWYRGSKLIQTAGNLTYLDEEVDINGTHTYTCNVSNPVSWESHTLNLTQDCQNAHQEFR

分子量

35-60 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
2B4/CD244 Protein, Human (200a.a, HEK293, His)
目录号:
HY-P72745
需求量: