2. 重组蛋白
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins
  5. TNF Receptor Superfamily 4-1BB/CD137
  6. 4-1BB
  7. 4-1BB/TNFRSF9 蛋白, Mouse (isoform 2, HEK293, His)

4-1BB/TNFRSF9 蛋白, Mouse (isoform 2, HEK293, His)

目录号: HY-P77574
产品使用指南

4-1BB/TNFRSF9 蛋白对于细胞因子和蛋白质结合至关重要，影响白细胞介素调节和细胞增殖等过程。它位于质膜外部，在成人胎盘中表达量特别高 (RPKM 139.4)，强调了它在特定生理环境中的重要性。作为人类 TNFRSF9 的直系同源物，它表明跨物种功能的进化保守性。4-1BB/TNFRSF9 蛋白, Mouse (isoform 2, HEK293, His) 是重组的 4-1BB/TNFRSF9 蛋白，由 HEK293 表达，带有 C-His 标签。4-1BB/TNFRSF9 蛋白, Mouse (isoform 2, HEK293, His) 全长 188 个氨基酸，分子量为 40-50 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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描述

4-1BB/TNFRSF9 Protein, crucial with cytokine and protein binding, influences processes like interleukin regulation and cell proliferation. Located externally on the plasma membrane, its expression is notably high in the placenta adult (RPKM 139.4), emphasizing its significance in specific physiological contexts. As the ortholog to human TNFRSF9, it suggests evolutionary conservation of functions across species. 4-1BB/TNFRSF9 Protein, Mouse (isoform 2, HEK293, His) is the recombinant mouse-derived 4-1BB/TNFRSF9 protein, expressed by HEK293 , with C-His labeled tag. The total length of 4-1BB/TNFRSF9 Protein, Mouse (isoform 2, HEK293, His) is 188 a.a., with molecular weight of 40-50 kDa.
研究背景

4-1BB/TNFRSF9 蛋白具有重要的功能，包括细胞因子结合活性、相同蛋白结合活性和信号受体活性。它在各种过程的上游或内部发挥作用，例如白介素 10 产生的负调节、白介素 12 产生的负调节以及细胞群增殖的调节。该蛋白质战略性地位于质膜和细胞外空间的外侧。它表现出有限的表达，在成人胎盘中尤其突出（RPKM 139.4），强调了其在特定生理环境中的重要性。4-1BB/TNFRSF9 是人类 TNFRSF9（TNF 受体超家族成员 9）的直系同源对应物，表明其功能在跨物种中具有进化保守性。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

NP_001070976 (V24-L211)
基因 ID

21942  [NCBI]
蛋白结构
N-term
4-1BB (V24-L211)
Accession # NP_001070976
His
C-term
同用名
CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
分子量

40-50 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

4-1BB/TNFRSF9 Protein, Mouse (isoform 2, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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