ADAM8 蛋白, Human (HEK293, His)

ADAM8 protein is suggested to be involved in leukocyte extravasation, indicating its potential role in facilitating the migration of white blood cells from blood vessels into surrounding tissues. This implies ADAM8's contribution to immune responses by regulating leukocyte movement across the endothelial barrier, a crucial step in inflammatory and immune surveillance processes. ADAM8 Protein, Human (HEK293, His) is the recombinant human-derived ADAM8 protein, expressed by HEK293 , with C-His labeled tag. The total length of ADAM8 Protein, Human (HEK293, His) is 639 a.a., with molecular weight of ~71 kDa.

据推测 ADAM8 蛋白参与白细胞外渗过程，这意味着其在促进白细胞从血管迁移到周围组织中的潜在作用。这表明 ADAM8 可能通过调节白细胞穿过内皮屏障的运动来促进免疫反应，这是炎症和免疫监视过程中的一个重要步骤。

Immobilized Human ADAM8, His Tag at 0.5 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC₅₀ of ≤8.1 ng/mL determined by ELISA.

Human

HEK293

C-His

AAI15405.1 (I17-P655)

101  [NCBI]

Approximately 71 kDa

Greater than 95% as determined by reducing SDS-PAGE or Tris-Bis PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.