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  3. AG-2 蛋白, Mouse (His)

AG-2 蛋白, Mouse (His)

目录号: HY-P701076
产品使用指南

AG-2 蛋白是蛋白质二硫键异构酶家族的成员,预计会与肌营养不良聚糖、表皮生长因子受体和相同的蛋白质结合。它在消化道形态发生、粘液分泌和发育生长调节中发挥作用。AG-2 蛋白, Mouse (His) 是重组的 AG-2 蛋白,由 E. coli 表达,带有 C-His 标签。AG-2 蛋白, Mouse (His) 全长 155 个氨基酸,分子量为 18.82 kDa。

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描述

AG-2 protein is a member of the protein disulfide isomerase family and is predicted to bind to dystroglycan, epidermal growth factor receptor, and the same proteins. It plays a role in digestive tract morphogenesis, mucus secretion, and developmental growth regulation. AG-2 Protein, Mouse (His) is the recombinant mouse-derived AG-2 protein, expressed by E. coli , with C-His labeled tag. The total length of AG-2 Protein, Mouse (His) is 155 a.a., with molecular weight of 18.82 kDa.

研究背景

AG-2 编码前梯度 2,是蛋白质二硫键异构酶家族的成员,预计表现出肌营养不良聚糖结合活性、表皮生长因子受体结合活性和相同的蛋白质结合活性。这种蛋白质参与多种生物过程,包括消化道形态发生、粘液分泌和发育生长的正向调节。AG-2 位于内质网中,并在各种组织中表现出偏向表达,其中在成人的大肠和结肠中显着流行。与人类 AGR2 的直系同源关系强调了其进化保守性,表明其具有共同的功能作用以及对细胞和发育过程的潜在贡献。

种属

Mouse

表达系统

E. coli

标签

C-His

蛋白编号

NP_035913.1 (K21-L175)

基因 ID

23795  [NCBI]

蛋白结构
N-term
AG-2 (K21-L175)
Accession # NP_035913.1
His
C-term
同用名
Anterior gradient protein 2 homolog; AG-2; AG2; hAG-2; hAG 2; HPC8; AGR2
分子量

18.82 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

AG-2 Protein, Mouse (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
AG-2 Protein, Mouse (His)
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HY-P701076
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