AGRP 蛋白, Mouse (50a.a, HEK293, Fc)

The AGRP protein, encoded by the AGRP gene, regulates feeding behavior and body weight. It acts as a melanocortin receptor signaling antagonist, influencing appetite and metabolic balance. AGRP has multiple splice variants, adding to its regulatory complexity. Its expression extends beyond the central nervous system, with presence in tissues like the testis and placenta, indicating systemic involvement in physiological processes. AGRP Protein, Mouse (50a.a, HEK293, Fc) is the recombinant mouse-derived AGRP protein, expressed by HEK293 , with N-hFc labeled tag. The total length of AGRP Protein, Mouse (50a.a, HEK293, Fc) is 50 a.a., with molecular weight of 35-40 kDa.

AGRP 基因编码一种对调节摄食行为至关重要的蛋白质，并在控制体重方面发挥关键作用。作为黑皮质素受体信号传导的拮抗剂，编码的蛋白质参与控制食欲和代谢平衡的复杂途径。该基因的多个选择性剪接转录变体已被鉴定，导致其调节功能的复杂性。AGRP 的表达很广泛，在各种组织中都观察到存在，包括成人的睾丸和胎盘，表明它全身参与中枢神经系统以外的生理过程。

Data is not available.

Mouse

HEK293

N-hFc

NP_031453.1 (S82-T131)

11604  [NCBI]

SPRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTATNLCSRT

Approximately 35-40 kDa due to the glycosylation.

• 
  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.