1. 重组蛋白
  2. Enzymes & Regulators Biotinylated Proteins
  3. Transferases (EC 2) Serine/Threonine Kinase Proteins
  4. ALK 蛋白, Human (L1196M, Biotinylated, sf9, Avi)

ALK 蛋白, Human (L1196M, Biotinylated, sf9, Avi)

目录号: HY-P702715
产品使用指南 技术支持

ALK 蛋白, Human (L1196M, Biotinylated, sf9, Avi) 是重组的 ALK 蛋白,由 Sf9 insect cells 表达,带有 Avi 标签。

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SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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描述

ALK Protein, Human (L1196M, Biotinylated, sf9, Avi) is the recombinant human-derived ALK, expressed by Sf9 insect cells, with Avi labeled tag.

研究背景

ALK 是一种短暂表达于特定神经系统区域的神经元受体酪氨酸激酶,在神经发生和分化中起关键作用。该蛋白还通过调控白色脂肪组织脂解和交感神经张力参与能量稳态维持(By similarity)。被 ALKAL2(而非 ALKAL1)激活后,通过 MAPK 通路启动细胞内信号传导,磷酸化 CBL、FRS2、IRS1 和 SHC1 等靶点。ALK 可能还受 pleiotrophin (PTN) 和 midkine (MDK) 调控,二者通过 MAPK/PI3K 通路促进抗凋亡信号和细胞增殖。此外,ALK 通过 IRS1-AKT 驱动 NF-κB 激活,这对 MDK 介导的自分泌生长和存活至关重要。

种属

Human

表达系统

Sf9 insect cells

标签

Avi

蛋白编号

Q9UM73 (V1058-P1620, L1196M)

基因 ID

238

蛋白长度

Partial

中文名
生物素化 ALK 蛋白
同用名
ALK; anaplastic lymphoma receptor tyrosine kinase; anaplastic lymphoma kinase (Ki 1); ALK tyrosine kinase receptor; CD246; CD246 antigen; mutant anaplastic lymphoma kinase; NBLST3;
纯度

Greater than 80 % as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ALK Protein, Human (L1196M, Biotinylated, sf9, Avi)
目录号:
HY-P702715
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