Alpha-2-Antiplasmin/Serpin F2 蛋白, Cynomolgus (HEK293, His)

Alpha-2-antiplasmin/serpin F2 protein is a member of the serine protease inhibitor family and can significantly inhibit plasmin to regulate thrombolysis. Synthesized in the liver and circulating in the blood, it prevents excessive fibrinolysis and ensures clot stabilization. Alpha-2-Antiplasmin/Serpin F2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alpha-2-Antiplasmin/Serpin F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Alpha-2-Antiplasmin/Serpin F2 Protein, Cynomolgus (HEK293, His) is 464 a.a., with molecular weight of 60-70 kDa.

Alpha-2-抗纤溶酶/丝氨酸蛋白酶抑制剂 F2 蛋白属于丝氨酸蛋白酶抑制剂家族，是一组调节蛋白酶活性的蛋白质。它在抑制纤溶酶（一种参与血栓溶解的蛋白酶）方面发挥着至关重要的作用。通过抑制纤溶酶，Alpha-2-抗纤溶酶/丝氨酸蛋白酶抑制剂 F2 可防止过度纤维蛋白溶解，并有助于维持血栓的稳定性。这种蛋白质主要在肝脏中合成并在血液中循环。Alpha-2-抗纤溶酶/丝氨酸蛋白酶抑制剂 F2 的缺乏或失调可导致纤维蛋白溶解增加和出血性疾病的风险更高。此外，这种蛋白质还与其他生物过程有关，例如炎症和组织重塑。更深入地了解 Alpha-2-抗纤溶酶/丝氨酸蛋白酶抑制剂 F2 的功能和调节可以为凝血障碍和涉及异常蛋白酶活性的其他疾病的治疗开发提供见解。

1.Immobilized Cynomolgus SERPINF2, His Tag at 1 μg/mL (100 μl/Well) on the plate. Dose response curve for Anti-SERPINF2 Antibody, hFc Tag with the EC₅₀ of ≤1 μg/mL determined by ELISA.
2.Immobilized Cynomolgus SERPINF2, His Tag at 2 μg/mL (100 μl/Well) on the plate. Dose response curve for Anti-SERPINF2 Antibody, hFc Tag with the EC₅₀ of ≤55 ng/mL determined by ELISA.

Cynomolgus

HEK293

C-His

A0A2K5WNU6 (M27-K490)

102116557

60-70 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.