Animal-Free CD70 蛋白, Mouse (His)

The CD70 Protein, a prominent member of the tumor necrosis factor family, plays a crucial role in immune regulation and cellular responses. Its study enhances our understanding of immune modulation, offering potential applications in immunological assays and therapies. CD70's classification within the tumor necrosis factor family underscores its unique contributions to T cell activation and co-stimulation. Further exploration promises to enhance our knowledge of its role in both normal immune function and pathological conditions. Animal-Free CD70 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeCD70 protein, expressed by E. coli, with N-His, N-His labeled tag. The total length of Animal-Free CD70 Protein, Mouse (His) is 149 a.a., with molecular weight of ~17.25 kDa.

CD70 蛋白是肿瘤坏死因子家族的重要成员，凸显了其在免疫调节和细胞反应中的关键作用。作为该家族的一部分，CD70 可能与相关蛋白具有保守的结构和功能特征，强调其参与与免疫调节相关的信号通路。肿瘤坏死因子家族的分类强调了其在更广泛的细胞因子背景下的特定名称，从而深入了解其对 T 细胞激活和共刺激的独特贡献。CD70 的研究有助于我们了解其在免疫稳态中的作用，为各种免疫学测定和不含动物源性成分的治疗开发提供潜在应用。对 CD70 作用的进一步探索有望增强我们对其对正常免疫功能和病理状况的贡献的了解。

Measure by its ability to induce proliferation in mouse T cells in the presence of the anti-CD3 antibody. The ED₅₀ for this effect is <4.5 μg/mL.

Mouse

E. coli

N-His;N-His

Q05A52 (Q47-P195)

21948  [NCBI]

QQQRLLEHPEPHTAELQLNLTVPRKDPTLRWGAGPALGRSFTHGPELEEGHLRIHQDGLYRLHIQVTLANCSSPGSTLQHRATLAVGICSPAAHGISLLRGRFGQDCTVALQRLTYLVHGDVLCTNLTLPLLPSRNADETFFGVQWICP

Approximately 17.25 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH7.4.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.