Animal-Free Enterokinase 蛋白, Bovine (P. pastoris, His)

Enterokinase proteins play a key role in initiating the activation of pancreatic proteolytic enzymes, including trypsin, chymotrypsin, and carboxypeptidase A. Its catalytic function converts trypsinogen to trypsin, triggering the cascade activation of chymotrypsinogen, procarboxypeptidase, and tropoelastin. Animal-Free Enterokinase Protein, Bovine (His) is the recombinant bovine-derived Enterokinase, expressed by P. pastoris, with C-His labeled tag. The total length of Animal-Free Enterokinase Protein, Bovine (His) is 235 a.a..

Enterokinase 是一种糖蛋白，主要存在于十二指肠和空肠黏膜中。Enterokinase 的核心作用是激活消化酶原，可将胰蛋白酶原转化为胰蛋白酶。激活后的胰蛋白酶不仅能直接分解蛋白质，还能进一步激活其他酶原，如糜蛋白酶原、羧肽酶原和弹性蛋白酶原等，形成消化酶级联反应，促进蛋白质消化^[1][2]。

Bovine

P. pastoris

C-His

P98072-1 (I801-H1035)

282009

Full Length of Enteropeptidase catalytic light chain

/

Approximately 40 kDa,based on SDS-PAGE under reducing conditions.

Greater than 95% as determined by reducing SDS-PAGE

< 1 EU/μg of protein by gel clotting method

• [1]. Mann NS, et al. Enterokinase. Proc Soc Exp Biol Med. 1994 Jun;206(2):114-8.  [Content Brief]

  [2]. Kitamoto Y, et al. Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7588-92.  [Content Brief]