Animal-Free GRO-alpha/CXCL1 蛋白, Mouse (His)

GRO-alpha (CXCL1) Protein, with chemotactic properties, attracts and activates neutrophils during inflammatory responses. This hematoregulatory chemokine also suppresses hematopoietic progenitor cell proliferation, emphasizing its intricate role in hematopoiesis regulation. The truncated form KC(5-72) notably exhibits significantly enhanced hematopoietic activity in vitro. Animal-Free GRO-alpha/CXCL1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeGRO-alpha/CXCL1 protein, expressed by E. coli , with tag free. The total length of Animal-Free GRO-alpha/CXCL1 Protein, Mouse (His) is 68 a.a., with molecular weight of ~7.45 kDa.

GRO-alpha (CXCL1) 蛋白具有趋化特性，可吸引中性粒细胞并在炎症反应期间促进其激活。此外，这种血液调节趋化因子显示出抑制造血祖细胞增殖的能力，突出了其在调节造血中的复杂作用。值得注意的是，截短形式的KC(5-72)在体外表现出显着增强的造血活性。

The ED₅₀ is <15 ng/mL as measure by its ability to chemoattract BaF3 cells transfected with human CXCR2.

Mouse

E. coli

Tag Free

P12850 (N29-K96)

14825  [NCBI]

NELRCQCLQTMAGIHLKNIQSLKVLPSGPHCTQTEVIATLKNGREACLDPEAPLVQKIVQKMLKGVPK

Approximately 7.45 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 50 mM Tris and 150 mM NaCl, pH 8.5.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 10 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.