Animal-Free TNFRSF12A 蛋白, Mouse (His)

TNFRSF12A Protein, a receptor for TNFSF12/TWEAK, exhibits a weak apoptosis-inducing ability in specific cells. It promotes angiogenesis and endothelial cell proliferation, and may modulate cellular adhesion to matrix proteins. In functional interactions, TNFRSF12A associates with TRAF1 and TRAF2, possibly with TRAF3, suggesting its involvement in signaling pathways contributing to diverse cellular processes. Animal-Free TNFRSF12A Protein, Mouse (His) is the recombinant mouse-derived animal-FreeTNFRSF12A protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free TNFRSF12A Protein, Mouse (His) is 156 a.a., with molecular weight of ~18.14 kDa.

TNFRSF12A 蛋白作为 TNFSF12/TWEAK 的受体，在某些细胞类型中诱导细胞凋亡的能力较弱。此外，它还具有促进血管生成和刺激内皮细胞增殖的作用。TNFRSF12A 还可以调节细胞对基质蛋白的粘附。在其功能相互作用中，TNFRSF12A 与 TRAF1 和 TRAF2 相关，也可能与 TRAF3 相关，表明它参与了有助于各种细胞过程的信号传导途径。

Measure by its ability to induce proliferation in HUVEC cells. The ED₅₀for this effect is <0.2 μg/mL.

Mouse

E. coli

C-His

Q9CR75 (S94-H249)

27279  [NCBI]

MSAPKGRKARPRRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEETKINSSSPLRYDRQIGEFTVIRAGLYYLYCQVHFDEGKAVYLKLDLLVNGVLALRCLEEFSATAASSPGPQLRLCQVSGLLPLRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH

Approximately 18.14 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing in 1X PBS, pH 7.4.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.