Apolipoprotein H/APOH 蛋白, Cynomolgus (HEK293, His)

Apolipoprotein H/APOH proteins have multiple functions and can bind to negatively charged substances such as heparin and phospholipids. Its diverse interactions highlight the adaptability that is critical for preventing activation of the intrinsic coagulation cascade by binding to phospholipids on the surface of damaged cells. Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Apolipoprotein H/APOH protein, expressed by HEK293 , with C-His labeled tag. The total length of Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) is 326 a.a., with molecular weight of 50-65 kDa.

载脂蛋白 H/APOH 蛋白表现出多种功能，因为它可以与各种带负电的物质结合，包括肝素、磷脂和硫酸葡聚糖。它与这些物质的相互作用表明了广泛的分子参与，突出了它的适应性。值得注意的是，载脂蛋白 H/APOH 通过与受损细胞表面的磷脂特异性结合，在防止内在凝血级联的激活中发挥着至关重要的作用。这一功能强调了其对凝血过程调节的潜在贡献及其在响应细胞损伤时维持止血平衡的重要性。

Immobilized Cynomolgus APOH, His Tag at 1 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-APOH Antibody, hFc Tag with the EC₅₀ of ≤65 ng/mL determined by ELISA.

Cynomolgus

HEK293

C-His

XP_045230479.1 (G20-C345)

102134518  [NCBI]

50-65 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, 100mM Arginine, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.