B3GALTL 蛋白, Human (HEK293, His)

B3GALTL Protein s a novel glycosyltransferase found in multicellular animals such as mammals, insects, and nematodes. B3GALTL plays important roles in variety of biological processes and encodes enzymes that catalyze the attachment of asugar molecule to specific acceptor sites. And it is involved in the synthesis of the disaccharide Glc-β1,3-Fuc-O-. Furthermore, mutations in the B3GALTL gene cause Peters Plus syndrome. B3GALTL Protein, Human (HEK293, His) is the recombinant human-derived B3GALTL protein, expressed by HEK293 , with N-His labeled tag. The total length of B3GALTL Protein, Human (HEK293, His) is 466 a.a., with molecular weight of ~56 kDa.

B3GALTL 是一种新型糖基转移酶，存在于哺乳动物、昆虫和线虫等多细胞动物中。B3GALTL 在各种生物过程中发挥重要作用，并编码催化 asugar 分子附着到特定受体位点的酶。B3GALTL 参与二糖 Glc-β1,3-Fuc-O- 的合成，该合成发生在许多生物学重要分子的血小板反应蛋白 1 型重复序列 (TSR) 上。它存在于许多人类和小鼠组织中，其中心脏、肾脏和大脑是这两个物种的主要表达位点。B3GALTL 基因突变会导致彼得斯加综合征 (Peters Plus syndrome)。此外，B3GALTL 在甲状腺嗜酸细胞肿瘤中过度表达^[1][2]。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

N-10*His

JC8008 (S29-F494)

/

SEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTVFKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIFVAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQHLLSCYDSGKPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQVPISFHKHWNIDPVKVYFTWLAPSDEDKARQETQKGF

Approximately 56 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.