2. 重组蛋白
  3. Immune Checkpoint Proteins CD Antigens Biotinylated Proteins
  4. Inhibitory Checkpoint Molecules Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins
  5. B7-1/CD80
  6. B7-1/CD80 蛋白, Mouse (Biotinylated, HEK293, His)

B7-1/CD80 蛋白, Mouse (Biotinylated, HEK293, His)

目录号: HY-P77523
产品使用指南

B7-1/CD80 蛋白对于激活 T 淋巴细胞至关重要，可与 CD28 或 CTLA-4 受体结合，诱导增殖和细胞因子产生。这种相互作用调节免疫反应并影响 T 淋巴细胞的激活和功能。作为关键检查点，B7-1/CD80 协调信号事件，控制免疫系统的动态反应。B7-1/CD80 蛋白, Mouse (Biotinylated, HEK293, His) 是重组的 B7-1/CD80 蛋白，由 HEK293 表达，带有 C-His 标签。B7-1/CD80 蛋白, Mouse (Biotinylated, HEK293, His) 全长 245 个氨基酸，分子量约为 ~25.1 KDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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100 μg   询价  

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描述

B7-1/CD80 Protein, crucial in activating T lymphocytes, engages CD28 or CTLA-4 receptors, inducing proliferation and cytokine production. This interaction regulates immune responses and influences T lymphocyte activation and function. Serving as a key checkpoint, B7-1/CD80 orchestrates signaling events, controlling the immune system's dynamic responses. B7-1/CD80 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived B7-1/CD80 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-1/CD80 Protein, Mouse (Biotinylated, HEK293, His) is 245 a.a., with molecular weight of ~25.1 KDa.
研究背景

B7-1/CD80 蛋白在 T 淋巴细胞激活所需的共刺激信号中发挥着关键作用。它与 CD28 或 CTLA-4 受体的结合对于诱导 T 细胞增殖和细胞因子产生至关重要。B7-1/CD80 与这些受体之间的相互作用协调关键信号事件，调节免疫反应，影响 T 淋巴细胞的激活和功能。这种分子相互作用是控制免疫系统动态反应的复杂细胞信号网络中的关键检查点。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

Q00609 (M1-K245)
基因 ID

12519  [NCBI]
蛋白结构
N-term
B7-1 (M1-K245)
Accession # Q00609
His
C-term
同用名
T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; B7; CD80; CD28LG; LAB7
分子量

Approximately 25.1 kDa.
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

B7-1/CD80 Protein, Mouse (Biotinylated, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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