1. 重组蛋白
  2. Immune Checkpoint Proteins
  3. Stimulatory Immune Checkpoint Molecules
  4. B7-H6
  5. B7-H6 蛋白, Rat (HEK293, His)

B7-H6 蛋白, Rat (HEK293, His)

目录号: HY-P75483
产品使用指南

B7-H6 是一种独特的单体蛋白,能够独特地触发 NCR3 依赖性自然杀伤 (NK) 细胞激活,与 NCR3 特异性相互作用,同时避免与其他 NK 细胞激活受体(NCR1、NCR2 和 KLRK1)结合。这种特异性强调了 B7-H6 在通过 NK 细胞激活机制的复杂网络中的 NCR3 途径启动 NK 细胞反应方面的独特作用。B7-H6 蛋白, Rat (HEK293, His) 是重组的 B7-H6 蛋白,由 HEK293 表达,带有 C-His 标签。B7-H6 蛋白, Rat (HEK293, His) 全长 308 个氨基酸,分子量约为 ~35.1 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

B7-H6, a distinctive monomeric protein, uniquely triggers NCR3-dependent natural killer (NK) cell activation, specifically interacting with NCR3 while avoiding engagement with other NK cell-activating receptors (NCR1, NCR2, and KLRK1). This specificity underscores B7-H6's unique role in initiating NK cell responses through the NCR3 pathway within the intricate network of NK cell activation mechanisms. B7-H6 Protein, Rat (HEK293, His) is the recombinant rat-derived B7-H6 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-H6 Protein, Rat (HEK293, His) is 308 a.a., with molecular weight of ~35.1 kDa.

研究背景

B7-H6 是一种独特的蛋白质,可作为 NCR3 依赖性自然杀伤 (NK) 细胞激活的触发因素。作为单体,B7-H6 表现出与 NCR3 的特异性相互作用,明显避免与其他 NK 细胞激活受体(例如 NCR1、NCR2 和 KLRK1)结合。这种相互作用凸显了其在通过 NCR3 途径启动 NK 细胞反应中的独特作用,展示了其在 NK 细胞激活机制的复杂网络中的特异性。

种属

Rat

表达系统

HEK293

标签

C-His

蛋白编号

XP_006223356 (M1-S308)

基因 ID

691092  [NCBI]

蛋白结构
N-term
B7-H6 (M1-S308)
Accession # XP_006223356
His
C-term
同用名
Natural cytotoxicity triggering receptor 3 ligand 1; B7-H6; NCR3LG1
分子量

Approximately 35.1 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

B7-H6 Protein, Rat (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
B7-H6 Protein, Rat (HEK293, His)
目录号:
HY-P75483
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