BAK1 蛋白, Human

BAK1 Protein, Human is the recombinant human-derived BAK1, expressed by E. coli, with tag free labeled tag.

Bak 是一种在线粒体凋亡过程中起关键作用的蛋白质。当细胞接收到死亡信号时，Bak 通过寡聚化在线粒体外膜 (MOM) 上形成孔道，促进 MOM 通透性改变。这一过程导致凋亡相关因子 (如细胞色素 c) 释放到细胞质中，进而激活 caspase 9，并最终促使效应 caspases 的激活。

Human

E. coli

Tag Free

Q16611 (A2-G186)

578

Partial

20.5 kDa

Greater than 90% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl, 200 mM NaCl, 20% glycerol, 1 mM DTT, pH 7.5 or 50 mM HEPES (pH 7.5), 200 mM NaCl, 1 mM DTT.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.