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  4. BAMBI/NMA 蛋白, Mouse (HEK293, Fc)

BAMBI/NMA 蛋白, Mouse (HEK293, Fc)

目录号: HY-P74391
产品使用指南

BAMBI/NMA 蛋白充当负调节因子，控制 TGF-β 信号传导并调节复杂网络内的细胞反应。其调节作用确保平衡和受控的信号级联，使 BAMBI/NMA 成为微调受 TGF-β 影响的细胞结果的关键角色。这凸显了其在维持参与各种生理过程的信号通路的微妙平衡方面的重要性。BAMBI/NMA 蛋白, Mouse (HEK293, Fc) 是重组的 BAMBI/NMA 蛋白，由 HEK293 表达，带有 C-hFc 标签。BAMBI/NMA 蛋白, Mouse (HEK293, Fc) 全长 126 个氨基酸，分子量约为 ~45 kDa。

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描述

BAMBI/NMA Protein acts as a negative regulator, controlling TGF-beta signaling and modulating cellular responses within the intricate network. Its regulatory role ensures a balanced and controlled signaling cascade, making BAMBI/NMA a key player in fine-tuning cellular outcomes influenced by TGF-beta. This highlights its significance in maintaining the delicate balance of signaling pathways involved in various physiological processes. BAMBI/NMA Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived BAMBI/NMA protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BAMBI/NMA Protein, Mouse (HEK293, Fc) is 126 a.a., with molecular weight of ~45 kDa.
研究背景

BAMBI/NMA 蛋白作为 TGF-β 信号传导的负调节因子，对与这一关键细胞通信网络相关的复杂途径进行控制。通过其调节作用，BAMBI/NMA 有助于调节 TGF-β 介导的细胞反应，确保信号级联的平衡和受控。这种负调节功能使 BAMBI/NMA 成为微调受 TGF-β 影响的细胞结果的关键参与者，突出了其在维持各种生理过程中涉及的信号通路的微妙平衡方面的重要性。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

Q9D0L6 (M27-A152)
基因 ID

68010  [NCBI]
蛋白结构
N-term
BAMBI (M27-A152)
Accession # Q9D0L6
hFc
C-term
同用名
BMP and activin membrane-bound inhibitor homolog; BAMBI; NMA
分子量

Approximately 45 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

BAMBI/NMA Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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