2. 重组蛋白
  3. Cytokines and Growth Factors CAR-T related Proteins CD Antigens Biotinylated Proteins Fluorescent-labeled Recombinant Proteins
  4. TNF Superfamily B Cell CD Proteins
  5. TNF Receptor Superfamily BCMA/CD269
  6. B Cell Maturation Antigen (BCMA)
  7. BCMA/TNFRSF17 蛋白, Human (FITC, HEK293, His-Avi)

BCMA/TNFRSF17 蛋白, Human (FITC, HEK293, His-Avi)

目录号: HY-P700663
产品使用指南

BCMA/TNFRSF17 蛋白是 TNFSF13B/BLyS/BAFF 和 TNFSF13/APRIL 的受体，对促进 B 细胞存活和调节体液免疫至关重要。BCMA/TNFRSF17 激活 NF-kappa-B 和 JNK，在免疫反应信号通路中发挥着关键作用。它与 TRAF1、TRAF2、TRAF3、TRAF5 和 TRAF6 相关，表明参与这些接头蛋白介导的各种细胞过程。BCMA/TNFRSF17 蛋白, Human (FITC, HEK293, His-Avi) 是重组的 BCMA/TNFRSF17 蛋白，由 HEK293 表达，带有 C-Avi, C-His 标签。BCMA/TNFRSF17 蛋白, Human (FITC, HEK293, His-Avi) 全长 54 个氨基酸，分子量分别为 12 kDa & 15-17 kDa。

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描述

BCMA/TNFRSF17 Protein, a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL, crucially promotes B-cell survival and regulates humoral immunity. Activating NF-kappa-B and JNK, BCMA/TNFRSF17 plays a pivotal role in immune response signaling pathways. It associates with TRAF1, TRAF2, TRAF3, TRAF5, and TRAF6, indicating involvement in various cellular processes mediated by these adaptor proteins. BCMA/TNFRSF17 Protein, Human (FITC, HEK293, His-Avi) is the recombinant human-derived BCMA/TNFRSF17 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of BCMA/TNFRSF17 Protein, Human (FITC, HEK293, His-Avi) is 54 a.a., with molecular weight of 12 kDa & 15-17 kDa, respectively.
研究背景

BCMA/TNFRSF17 蛋白作为 TNFSF13B/BLyS/BAFF 和 TNFSF13/APRIL 的受体，在促进 B 细胞存活和调节体液免疫方面发挥重要作用。通过激活 NF-kappa-B 和 JNK，BCMA/TNFRSF17 在与免疫反应相关的信号通路中发挥着关键作用。此外，它与 TRAF1、TRAF2、TRAF3、TRAF5 和 TRAF6 形成关联，表明它参与这些接头蛋白介导的各种细胞过程。
种属

Human
表达系统

HEK293
标签

C-Avi;C-His
蛋白编号

Q02223 (M1-A54)
基因 ID

608  [NCBI]
蛋白结构
N-term
BCMA (M1-A54)
Accession # Q02223
His-Avi
C-term
同用名
CD269; TNFRSF17; BCMA; BCM; TNFRSF13A
分子量

12 kDa & 15-17 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

BCMA/TNFRSF17 Protein, Human (FITC, HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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