1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Stem Cell CD Proteins Platelet CD Proteins
  4. TPO-R/CD110
  5. C-MPL 蛋白, Rat (sf9, His)

C-MPL 蛋白, Rat (sf9, His)

目录号: HY-P74243
产品使用指南

C-MPL 蛋白是血小板生成素的受体,是一种在人类中由骨髓增殖性白血病病毒致癌基因编码的蛋白。C-MPL Protein参与 JAK/STAT/MAPK信号通路的激活。C-MPL 蛋白是血小板减少症的生物标志物。C-MPL 蛋白, Rat (sf9, His) 是重组的 C-MPL 蛋白,由 Sf9 insect cells 表达,带有 C-His 标签。C-MPL 蛋白, Rat (sf9, His) 全长 500 个氨基酸,分子量约为 ~55 kDa。

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1.  客户无需承担相应的运输费用。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

The C-MPL Protein, a receptor for thrombopoietin, is a protein encoded in humans by the oncogene of myeloproliferative leukemia virus. The C-MPL Protein is involved in the activation of the JAK/STAT/MAPK signaling pathway. C-MPL Protein is a biomarker for thrombocytopenia. C-MPL Protein, Rat (sf9, His) is the recombinant rat-derived C-MPL protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of C-MPL Protein, Rat (sf9, His) is 500 a.a., with molecular weight of ~55 kDa.

研究背景

血小板生成素受体也被称为骨髓增殖性白血病蛋白或 CD110 (分化簇110),是一种在人类中由骨髓增殖性白血病病毒致癌基因编码的蛋白。C-MPL 可激活血小板生成素受体,参与骨髓细胞稳态、血小板聚集和积极调节血小板形成过程。C-MPL 参与 家族蛋白的磷酸化。C-MPL 是血小板减少症的生物标志物。

种属

Rat

表达系统

Sf9 insect cells

标签

C-His

蛋白编号

XP_001072502 (M1-A500)

基因 ID
蛋白结构
N-term
C-MPL (M1-A500)
Accession # XP_001072502
His
C-term
同用名
CD110; c-Mpl; MPL; MPLV; Thrombopoietin R; TPO-R
分子量

Approximately 55 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
C-MPL Protein, Rat (sf9, His)
目录号:
HY-P74243
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