2. 重组蛋白
  3. Complement System
  4. Complement Component 1
  5. Complement Component 1s
  6. C1s-A subcomponent 蛋白, Mouse (HEK293, His)

C1s-A subcomponent 蛋白, Mouse (HEK293, His)

目录号: HY-P75463
COA 产品使用指南

C1s-A 亚成分蛋白是一种丝氨酸蛋白酶，在经典补体系统途径中至关重要。它与 C1q 和 C1r 结合形成 C1，启动补体激活。由 C1r 激活，C1s 随后可以触发下游组件 C2 和 C4，影响补体系统级联。C1s-A subcomponent 蛋白, Mouse (HEK293, His) 是重组的 C1s-A 亚组分蛋白，由 HEK293 表达，带有 C-His 标签。C1s-A subcomponent 蛋白, Mouse (HEK293, His) 全长 673 个氨基酸，分子量约为 ~76.6 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
Free Sample   Apply now  
5 μg ￥750 In-stock
10 μg ￥1200 In-stock
20 μg ￥1900 询价
50 μg ￥3600 In-stock
100 μg   询价  

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描述

C1s-A subcomponent protein, a serine protease, is pivotal in the classical complement system pathway. Partnering with C1q and C1r, it forms C1, initiating complement activation. Activated by C1r, C1s can subsequently trigger downstream components C2 and C4, influencing the complement system cascade. C1s-A subcomponent Protein, Mouse (HEK293, His) is the recombinant mouse-derived C1s-A subcomponent protein, expressed by HEK293, with C-His labeled tag. The total length of C1s-A subcomponent Protein, Mouse (HEK293, His) is 673 a.a., with molecular weight of ~76.6 kDa.
研究背景

C1s-A 亚组分蛋白是一种丝氨酸蛋白酶，在补体系统的经典途径中发挥着至关重要的作用。它与 C1q 和 C1r 结合形成 C1，即该途径的起始成分。被 C1r 激活后，C1s 能够激活下游成分 C2 和 C4，从而促进补体系统中的级联事件。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

Q8CG14 (E16-D688)
基因 ID

50908  [NCBI]
蛋白结构
N-term
C1s1 (E16-D688)
Accession # Q8CG14
His
C-term
同用名
Complement C1s-A subcomponent; C1 esterase; C1sa; C1s
分子量

Approximately 76.6 kDa
纯度

Greater than 85% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

C1s-A subcomponent Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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