2. 重组蛋白
  3. Receptor Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Cadherins
  6. LI-Cadherin/Cadherin-17
  7. Cadherin-17 蛋白, Human (765a.a, HEK293, hFc)

Cadherin-17 蛋白, Human (765a.a, HEK293, hFc)

目录号: HY-P700688
产品使用指南

Cadherin-17 蛋白通过优先与其他 Cadherin-17 分子结合来介导细胞间相互作用，对异质细胞类型进行分类和组织。 LI-钙粘蛋白是钙粘蛋白 17 的一种亚型，与肝脏和肠道的形态组织有关。 Cadherin-17 还促进肠肽转运，强调其功能意义。Cadherin-17 蛋白, Human (765a.a, HEK293, hFc) 是重组的 钙粘蛋白 17 蛋白，由 HEK293 表达，带有 C-hFc 标签。Cadherin-17 蛋白, Human (765a.a, HEK293, hFc) 全长 765 个氨基酸，分子量为 113-135 kDa。

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描述

Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is 765 a.a., with molecular weight of 113-135 kDa.
研究背景

Cadherin-17 蛋白是一种钙依赖性细胞粘附分子，参与介导细胞间相互作用。通过与连接细胞中相同类型的其他钙粘蛋白分子的优先同质相互作用，Cadherin-17 有助于异质细胞类型的分类和组织。具体而言，LI-钙粘蛋白（Cadherin-17 的一种亚型）可能在肝脏和肠道的形态组织中发挥作用。此外，Cadherin-17 还参与促进肠肽转运，突出了其在细胞过程中的功能重要性。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

Q12864 (Q23-M787)
基因 ID
蛋白结构
N-term
Cadherin-17 (Q23-M787)
Accession # Q12864
hFc
C-term
同用名
Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024
分子量

113-135 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Cadherin-17 Protein, Human (765a.a, HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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