1. 重组蛋白
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Immunoglobulin-like Cell Adhesion Molecules
  5. Cell Adhesion Molecule 3 (CADM3)
  6. CADM3 蛋白, Human (HEK293, His)

CADM3 蛋白, Human (HEK293, His)

目录号: HY-P70083
产品使用指南

CADM3 蛋白通过与 IGSF4、NECTIN1 和 NECTIN3 的不依赖于钙的同性和异性相互作用,对细胞间粘附至关重要。它可以通过与 EPB41L1 的相互作用来调节细胞与细胞的连接。CADM3 蛋白与 NECTIN3 形成同二聚体和反式异二聚体,并与 EPB41L1、DLG3、PALS2 和 CASK 相互作用。CADM3 蛋白, Human (HEK293, His) 是重组的 CADM3 蛋白,由 HEK293 表达,带有 C-6*His 标签。CADM3 蛋白, Human (HEK293, His) 全长 306 个氨基酸,分子量为 35-42 kDa。

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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100 μg   询价  

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描述

CADM3 Protein is crucial for cell-cell adhesion through calcium-independent homophilic and heterophilic interactions with IGSF4, NECTIN1, and NECTIN3. It can regulate cell-cell junctions through its interaction with EPB41L1. CADM3 Protein forms homodimers and trans-heterodimers with NECTIN3, and interacts with EPB41L1, DLG3, PALS2, and CASK. CADM3 Protein, Human (HEK293, His) is the recombinant human-derived CADM3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CADM3 Protein, Human (HEK293, His) is 306 a.a., with molecular weight of 35-42 kDa.

研究背景

CADM3 蛋白通过与 IGSF4、NECTIN1 和 NECTIN3 一起参与不依赖钙的同种细胞间粘附和不依赖钙的异嗜细胞粘附,在细胞间粘附中发挥关键作用。它与 EPB41L1 的相互作用有可能调节细胞-细胞连接的结构或功能(通过相似性)。CADM3 蛋白形成同二聚体,也可以与 NECTIN3 形成反式异二聚体。此外,CADM3 蛋白与 EPB41L1、DLG3、PALS2 和 CASK 相互作用(通过相似性)。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q8N126 (N25-H330)

基因 ID
蛋白结构
N-term
CADM3 (N25-H330)
Accession # Q8N126
6*His
C-term
同用名
rHuCell adhesion molecule 3/CADM3, His; Cell Adhesion Molecule 3; Brain Immunoglobulin Receptor; Immunoglobulin Superfamily Member 4B; IgSF4B; Nectin-Like Protein 1; NECL-1; Synaptic Cell Adhesion Molecule 3; SynCAM3; TSLC1-Like Protein 1; TSLL1; CADM3; IGSF4B; NECL1; SYNCAM3; TSLL1
氨基酸序列

NLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYH

分子量

35-42 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CADM3 Protein, Human (HEK293, His)
目录号:
HY-P70083
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