2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Peptide Hormone & Neuropeptides
  5. Calcitonin
  6. Calcitonin/CALCA 蛋白, Human (GST)

Calcitonin/CALCA 蛋白, Human (GST)

目录号: HY-P71702
产品使用指南

降钙素/CALCA 蛋白充当血管舒张剂，扩张不同的血管，包括冠状血管、脑血管和全身血管。它在中枢神经系统中的存在表明它作为神经递质或神经调节剂的潜在作用。Calcitonin/CALCA 蛋白, Human (GST) 是重组的 降钙素/CALCA 蛋白，由 E. coli 表达，带有 N-GST 标签。Calcitonin/CALCA 蛋白, Human (GST) 全长 36 个氨基酸，分子量约为 ~30.6 kDa。

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描述

Calcitonin/CALCA protein acts as a vasodilator, dilating different blood vessels, including coronary, cerebral, and systemic vessels. Its presence in the central nervous system suggests its potential role as a neurotransmitter or neuromodulator. Calcitonin/CALCA Protein, Human (GST) is the recombinant human-derived Calcitonin/CALCA protein, expressed by E. coli , with N-GST labeled tag. The total length of Calcitonin/CALCA Protein, Human (GST) is 36 a.a., with molecular weight of ~30.6 kDa.
研究背景

降钙素/CALCA 蛋白以其血管扩张剂的作用而闻名，可诱导各种血管扩张，包括冠状动脉、脑血管和全身血管。它在中枢神经系统中的存在表明其具有作为神经递质或神经调节剂的潜在功能。此外，降钙素/CALCA 有助于升高血小板 cAMP，表明其参与调节细胞内信号通路。降钙素/CALCA 的多方面作用强调了其在中枢神经系统内血管调节和神经传递中的重要性。
种属

Human
表达系统

E. coli
标签

N-GST
蛋白编号

P06881 (A83-A118)
基因 ID

796  [NCBI]
蛋白结构
N-term
GST
CALCA (A83-A118)
Accession # P06881
C-term
同用名
CALCA; CALC1Calcitonin gene-related peptide 1; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I
氨基酸序列

ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKA

分子量

Approximately 30.6 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Calcitonin/CALCA Protein, Human (GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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