CANT1 蛋白, Human (HEK293, Fc)

CANT1, a calcium-dependent nucleotidase, exhibits a pronounced preference for UDP, showcasing its enzymatic activity order as UDP > GDP > UTP > GTP. Notably, its activity towards ADP is minimal, and even lower towards ATP, while it does not hydrolyze AMP and GMP. This substrate specificity has been well-documented in various studies. Beyond its nucleotidase function, CANT1 is implicated in proteoglycan synthesis, underscoring its role in cellular processes related to the production of these essential macromolecules. The distinct substrate preferences and involvement in proteoglycan synthesis highlight the nuanced and specialized functions of CANT1 in cellular metabolism. CANT1 Protein, Human (HEK293, Fc) is the recombinant human-derived CANT1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CANT1 Protein, Human (HEK293, Fc) is 322 a.a., with molecular weight of ~65 kDa.

CANT1 是一种钙依赖性核苷酸酶，对 UDP 表现出明显的偏好，其酶活性顺序为 UDP > GDP > UTP > GTP。值得注意的是，它对 ADP 的活性很小，对 ATP 的活性甚至更低，但它不水解 AMP 和 GMP。这种底物特异性已在各种研究中得到充分证明。除了其核苷酸酶功能之外，CANT1 还参与蛋白聚糖合成，强调了其在与这些必需大分子的产生相关的细胞过程中的作用。不同的底物偏好和参与蛋白多糖合成突出了 CANT1 在细胞代谢中微妙和专门的功能。

Human

HEK293

N-hFc

Q8WVQ1 (G80-I401)

124583  [NCBI]

Approximately 65 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.