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  4. Cathelicidin-4/CATHL4 蛋白, Bovine (His-SUMO)

Cathelicidin-4/CATHL4 蛋白, Bovine (His-SUMO)

目录号: HY-P71468
产品使用指南

Cathelicidin-4/CATHL4蛋白具有强效杀菌活性，能有效针对金黄色葡萄球菌和大肠杆菌。这种抗菌能力使 cathelicidin-4 成为重要的先天免疫效应物，有助于宿主防御细菌病原体。Cathelicidin-4/CATHL4 蛋白, Bovine (His-SUMO) 是重组的 Cathelicidin-4/CATHL4 蛋白，由 E. coli 表达，带有 N-His, N-SUMO 标签。Cathelicidin-4/CATHL4 蛋白, Bovine (His-SUMO) 全长 13 个氨基酸，分子量约为 ~17.9 kDa。

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描述

Cathelicidin-4/CATHL4 protein has potent bactericidal activity and can effectively target Staphylococcus aureus and Escherichia coli. This antibacterial ability makes cathelicidin-4 an important innate immune effector that contributes to host defense against bacterial pathogens. Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) is the recombinant bovine-derived Cathelicidin-4/CATHL4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) is 13 a.a., with molecular weight of ~17.9 kDa.
研究背景

Cathelicidin-4/CATHL4 蛋白具有强大的杀菌活性，对金黄色葡萄球菌和大肠杆菌均有效。这种抗菌特性强调了 Cathelicidin-4 在宿主防御机制中的重要性，强调了其作为能够对抗细菌病原体的先天免疫效应器的作用。针对革兰氏阳性菌（金黄色葡萄球菌）和革兰氏阴性菌（大肠杆菌）的广谱抗菌活性强调了 Cathelicidin-4 的多功能性，使其成为宿主持续对抗微生物入侵者的重要组成部分。
种属

Bovine
表达系统

E. coli
标签

N-His;N-SUMO
蛋白编号

P33046 (131I-143R)
基因 ID

282166  [NCBI]
蛋白结构
N-term
6*His-SUMO
CATHL4 (131I-143R)
Accession # P33046
C-term
同用名
CATHL4; Cathelicidin-4; Indolicidin
氨基酸序列

ILPWKWPWWPWRR

分子量

Approximately 17.9 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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