1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CC Chemokines
  5. CCL6
  6. CCL6 蛋白, Rat (N-His)

CCL6 蛋白是间分泌β家族的一部分,是参与细胞间通讯和免疫反应的趋化因子的组成部分。在这个家族中,CCL6 可能在调节炎症过程和细胞相互作用中发挥重要作用。CCL6 蛋白, Rat (N-His) 是重组的 CCL6 蛋白,由 E. coli 表达,带有 N-6*His 标签。

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2 μg ¥650 In-stock
10 μg ¥1810 In-stock
50 μg ¥5060 In-stock
100 μg ¥8600 In-stock
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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The CCL6 protein is part of the intercrine beta family, a component of chemokines involved in intercellular communication and immune responses. In this family, CCL6 may play an important role in regulating inflammatory processes and cellular interactions. CCL6 Protein, Rat (N-His) is the recombinant rat-derived CCL6 protein, expressed by E. coli , with N-6*His labeled tag.

研究背景

CCL6 蛋白是间分泌 β(趋化因子 CC)家族的成员,将其置于一组因参与细胞间通讯和免疫反应而闻名的趋化因子中。作为间分泌 β 家族的一部分,CCL6 可能在调节炎症过程和细胞相互作用中发挥重要作用。有必要进一步探索,以揭示 CCL6 在趋化因子 CC 家族更广泛背景下的具体功能和影响,阐明其在介导免疫反应和促进细胞间信号传导动态网络中的重要性。

生物活性

Measured in a cell proliferation assay using HUVEC cells.The ED50 for this effect is 15.84 ng/mL, corresponding to a specific activity is 6.313×104 units/mg.

  • Measured in a cell proliferation assay using HUVEC cells.The ED50 for this effect is 15.84 ng/mL, corresponding to a specific activity is 6.313×104 units/mg.
种属

Rat

表达系统

E. coli

标签

N-6*His

蛋白编号

Q68FP3 (G22-A115)

基因 ID
蛋白结构
N-term
6*His
CCL6 (G22-A115)
Accession # Q68FP3
C-term
蛋白长度

Full Length of Mature Protein

中文名
CC趋化因子配体 6 蛋白
同用名
Ccl6C-C motif chemokine 6; Small-inducible cytokine A6
氨基酸序列

GLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA

分子量

Approximately 12 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of 50 mM Tris-HCl, 300 mM NaCl, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

CCL6 Protein, Rat (N-His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CCL6 Protein, Rat (N-His)
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HY-P700281
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