1. 重组蛋白
  2. Cytokines and Growth Factors Biotinylated Proteins
  3. IGF family
  4. CTGF
  5. CCN2/CTGF 蛋白, Human (Biotinylated, HEK293, His-Avi)

CCN2/CTGF 蛋白, Human (Biotinylated, HEK293, His-Avi)

目录号: HY-P78104
COA 产品使用指南

CCN2/CTGF(结缔组织生长因子)是一种主要由血管内皮细胞产生的蛋白质。它在各种细胞过程中发挥着重要作用。CCN2/CTGF 蛋白, Human (Biotinylated, HEK293, His-Avi) 是重组的 CCN2/CTGF 蛋白,由 HEK293 表达,带有 C-Avi, C-His 标签。CCN2/CTGF 蛋白, Human (Biotinylated, HEK293, His-Avi) 全长 323 个氨基酸,分子量为 43-55 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
20 μg ¥1950 In-stock
50 μg ¥4280 In-stock
100 μg   询价  

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描述

CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CCN2/CTGF Protein, Human (Biotinylated, HEK293, His-Avi) is 323 a.a., with molecular weight of 43-55 kDa.

研究背景

CCN2/CTGF(结缔组织生长因子)是一种主要由血管内皮细胞产生的蛋白质。它在各种细胞过程中发挥着重要作用。它的主要功能之一是吸引和刺激软骨细胞的增殖和分化,软骨细胞是参与软骨形成的细胞。此外,CCN2/CTGF 介导各种细胞类型的细胞粘附,包括成纤维细胞、肌成纤维细胞、内皮细胞和上皮细胞。这种粘附取决于肝素(一种多糖)和二价阳离子(例如钙或镁)的存在。此外,CCN2/CTGF 还能增强成纤维细胞生长因子(参与细胞生长和修复的蛋白质)诱导的 DNA 合成。总体而言,CCN2/CTGF 是一种重要的蛋白质,可调节软骨细胞功能、细胞粘附和 DNA 合成等细胞过程,有助于结缔组织的发育和维护。

生物活性

Immobilized Anti-CTGF Antibody at 2 ug/ml (100 ul /well) on the plate.Dose response curve for Biotinylated Human CTGF,His Tag with the EC50 of 33.4 ng/ml determined by ELISA.

种属

Human

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

Q5M8T4 (Q27-A349)

基因 ID
蛋白结构
N-term
CTGF (Q27-A349)
Accession # Q5M8T4
His-Avi
C-term
同用名
IGFBP8; IBP-8; CCN2; NOV2; HCS24; CTGF; CTGRP; Fisp12; MGC102839
分子量

43-55 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

CCN2/CTGF Protein, Human (Biotinylated, HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CCN2/CTGF Protein, Human (Biotinylated, HEK293, His-Avi)
目录号:
HY-P78104
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