2. 重组蛋白
  3. Fc Receptors
  4. Fc-gamma Receptor
  5. Fc gamma RIII/CD16
  6. Fc gamma RIII/CD16 蛋白, Mouse (185a.a, HEK293, His)

Fc gamma RIII/CD16 蛋白, Mouse (185a.a, HEK293, His)

目录号: HY-P70708
COA 产品使用指南

Fc gamma RIII/CD16 蛋白是 IgG1、IgG2a 和 IgG2b 的低亲和力受体，对于介导中性粒细胞响应 IgG 复合物的激活至关重要。它与 Fcgr4 冗余地发挥作用，并与 INPP5D/SHIP1 相互作用，强调其参与与免疫反应相关的细胞内信号传导途径。Fc gamma RIII/CD16 的重要性在于促进免疫球蛋白结合触发的细胞激活。Fc gamma RIII/CD16 蛋白, Mouse (185a.a, HEK293, His) 是重组的 Fc gamma RIII/CD16 蛋白，由 HEK293 表达，带有 C-6*His 标签。Fc gamma RIII/CD16 蛋白, Mouse (185a.a, HEK293, His) 全长 185 个氨基酸，分子量为 35-40 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 μg ￥930 In-stock
50 μg ￥2600 In-stock
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Fc gamma RIII/CD16 Protein, a low-affinity receptor for IgG1, IgG2a, and IgG2b, is crucial for mediating neutrophil activation in response to IgG complexes. It functions redundantly with Fcgr4 and interacts with INPP5D/SHIP1, emphasizing its involvement in intracellular signaling pathways linked to immune responses. Fc gamma RIII/CD16's significance lies in facilitating cellular activation triggered by immunoglobulin binding. Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His) is the recombinant mouse-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His) is 185 a.a., with molecular weight of 35-40 kDa.
研究背景

Fc gamma RIII/CD16 蛋白作为复合免疫球蛋白 gamma Fc 区的低亲和力受体，特异性结合 IgG1、IgG2a 和 IgG2b。该受体在介导中性粒细胞响应 IgG 复合物的激活中发挥着至关重要的作用，在此过程中与 Fcgr4 一起发挥冗余作用。与 INPP5D/SHIP1 的相互作用进一步凸显了其参与与免疫反应相关的细胞内信号通路，强调了其在促进免疫球蛋白结合触发的细胞激活中的重要性。
种属

Mouse
表达系统

HEK293
标签

C-6*His
蛋白编号

P08508 (A31-T215)
基因 ID

14131  [NCBI]
蛋白结构
N-term
CD16 (A31-T215)
Accession # P08508
6*His
C-term
同用名
Low affinity immunoglobulin gamma Fc region receptor III; Fcgr3; Fc gamma Receptor III; CD-antigen 16; CD16; FcRIII; IgG Fc receptor III
氨基酸序列

ALPKAVVKLDPPWIQVLKEDMVTLMCEGTHNPGNSSTQWFHNGRSIRSQVQASYTFKATVNDSGEYRCQMEQTRLSDPVDLGVISDWLLLQTPQRVFLEGETITLRCHSWRNKLLNRISFFHNEKSVRYHHYKSNFSIPKANHSHSGDYYCKGSLGSTQHQSKPVTITVQDPATTSSISLVWYHT

分子量

35-40 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (210 KB)

产品使用指南 (1213 KB)

Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His)
目录号：
HY-P70708
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z