1. 重组蛋白
  2. CD Antigens
  3. T Cell CD Proteins B Cell CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins
  4. CD1d
  5. CD1D2-B2M Heterodimer 蛋白, Mouse (HEK293, His)

CD1D2-B2M Heterodimer 蛋白, Mouse (HEK293, His)

目录号: HY-P76779
产品使用指南

CD1D2 蛋白作为抗原呈递分子发挥着至关重要的作用,结合自身和非自身糖脂并将其呈递给自然杀伤 T 细胞上的 T 细胞受体。它与 B2M 合作,介导免疫反应,并且它与 MHC II 和 CD74 的相互作用凸显了它在免疫系统调节的复杂网络中的重要性。CD1D2-B2M Heterodimer 蛋白, Mouse (HEK293, His) 是重组的蛋白二聚体复合物,包含 CD1D2-B2M 异二聚体蛋白,由 HEK293 表达,带有 C-His 标签。CD1D2-B2M Heterodimer 蛋白, Mouse (HEK293, His),分子量分别约为 ~33.7 & 11.7 KDa。

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1.  客户无需承担相应的运输费用。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

The CD1D2 protein plays a crucial role as an antigen-presenting molecule, binding self and non-self glycolipids and presenting them to T-cell receptors on natural killer T-cells. In partnership with B2M, it mediates immune responses, and its interactions with MHC II and CD74 highlight its significance in the complex network of immune system regulation. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D2-B2M Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His), has molecular weight of ~33.7 & 11.7 KDa, respectively.

研究背景

CD1D2-B2M 异二聚体蛋白作为关键的抗原呈递分子,能够结合自身和非自身糖脂,随后将它们呈递给自然杀伤 T 细胞上的 T 细胞受体。在与 B2M(β-2-微球蛋白)的异二聚体伙伴关系中,CD1D2 在介导免疫反应中发挥着至关重要的作用。值得注意的是,它与 MHC II 和 CD74 的相互作用进一步强调了它在复杂的免疫系统调节网络中的重要性。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

P11610 (Q22-G305)&P01887 (I21-M119)

基因 ID

12480  [NCBI]&12010  [NCBI]

同用名
Antigen-presenting glycoprotein CD1d2; Cd1d2; Beta-2-microglobulin
分子量

Approximately 33.7&11.7 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His)
目录号:
HY-P76779
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