1. 重组蛋白
  2. CD Antigens
  3. NK Cell CD Proteins Macrophage CD Proteins Erythrocyte CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins Cell Adhesion-related CD Proteins
  4. LFA-3/CD58
  5. CD2 蛋白, Cynomolgus (HEK293, His, solution)

CD2 蛋白, Cynomolgus (HEK293, His, solution)

目录号: HY-P75434
COA 产品使用指南

CD2 蛋白通过与 CD58 (LFA-3) 和 CD48/BCM1 相互作用介导 T 细胞与其他细胞类型的粘附。其胞质结构域参与 T 细胞触发,具有信号传导功能。CD2 还与 CD2AP 和 PSTPIP1 相互作用。此外,它与 FCGR3A 的相互作用可调节 NK 细胞活化和细胞毒性。CD2 蛋白, Cynomolgus (HEK293, His, solution) 是重组的 CD2 蛋白,由 HEK293 表达,带有 C-His 标签。CD2 蛋白, Cynomolgus (HEK293, His, solution) 全长 185 个氨基酸,分子量约为 ~35.7 kDa。

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重组蛋白定制服务

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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10 μg ¥1600 In-stock
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描述

CD2 Protein mediates T-cell adhesion to other cell types by interacting with CD58 (LFA-3) and CD48/BCM1. Implicated in T-cell triggering, its cytoplasmic domain has signaling functions. CD2 also interacts with CD2AP and PSTPIP1. Moreover, its interaction with FCGR3A modulates NK cell activation and cytotoxicity. CD2 Protein, Cynomolgus (HEK293, His, solution) is the recombinant cynomolgus-derived CD2 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD2 Protein, Cynomolgus (HEK293, His, solution) is 185 a.a., with molecular weight of ~35.7 kDa.

研究背景

CD2 是一种细胞表面糖蛋白,通过与淋巴细胞功能相关抗原 CD58 (LFA-3) 和 CD48/BCM1 相互作用,在介导 T 细胞和各种细胞类型之间的粘附方面发挥着至关重要的作用。除了其粘附功能外,CD2 还参与触发 T 细胞反应,其胞质结构域在信号传导通路中发挥作用。该蛋白与 CD48、CD58 (LFA-3)、CD2AP 和 PSTPIP1 相互作用,形成复杂的分子相互作用网络。此外,CD2 和 FCGR3A 之间的相互作用可调节 NK 细胞活化和细胞毒性,凸显其在免疫细胞功能中的多种参与。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

NP_001182402.1 (K25-D209)

基因 ID

677855

蛋白结构
N-term
CD2 (K25-D209)
Accession # NP_001182402.1
His
C-term
同用名
T-cell surface antigen CD2; LFA-2; CD2; SRBC
分子量

Approximately 35.7 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD2 Protein, Cynomolgus (HEK293, His, solution)
目录号:
HY-P75434
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