1. 重组蛋白
  2. CAR-T related Proteins CD Antigens
  3. B Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins
  4. CD20
  5. CD20/MS4A1 蛋白, Dog (HEK293, His, Nanodisc)

CD20/MS4A1 蛋白, Dog (HEK293, His, Nanodisc)

目录号: HY-P704448
产品使用指南 技术支持

CD20/MS4A1 蛋白-VLP,Dog,一种 B 淋巴细胞膜蛋白,对钙内流至关重要,对 B 淋巴细胞发育、分化和激活至关重要。作为钙库操纵 (SOC) 通道的组成部分,它在 B 细胞受体/BCR 激活时促进钙流入。CD20/MS4A1 蛋白, Dog (HEK293, His, Nanodisc) 是重组的 CD20/MS4A1 蛋白,由 HEK293 表达,带有 C-His 标签。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
20 μg ¥20580 1 - 2 周
100 μg ¥76440 1 - 2 周
> 100 μg   询价  

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描述

CD20/MS4A1 protein-VLP, Dog, a B lymphocyte membrane protein critical for calcium influx and essential for B lymphocyte development, differentiation, and activation. As a component of store-operated calcium (SOC) channels, it promotes calcium influx upon B cell receptor/BCR activation. CD20/MS4A1 Protein, Dog (HEK293, His, Nanodisc) is the recombinant dog-derived CD20/MS4A1 protein, expressed by HEK293, with C-His labeled tag.

研究背景

CD20/MS4A1 蛋白-VLP (Dog) 是一种 B 淋巴细胞特异性膜蛋白,在调节细胞钙流入方面发挥关键作用,而这对于 B 淋巴细胞的发育、分化和激活至关重要。作为钙库操纵 (SOC) 通道成分,它在 B 细胞受体/BCR 激活后促进钙流入。该蛋白质形成同源四聚体,有助于其结构组织和在钙信号传导中的功能作用。B 细胞受体复合物 CD20/MS4A1 蛋白-VLP(Dog)的一个组成部分,与细胞表面 IgM 的重链和轻链特异性相互作用,代表 BCR 的抗原结合成分。这种相互作用凸显了它在 B 细胞激活中的关键作用,并强调了它在协调免疫反应中的重要性。

种属

Dog

表达系统

HEK293

标签

C-His

蛋白编号

Q3C2E2 (M1-P297)

基因 ID

485430

蛋白结构
N-term
CD20 (M1-P297)
Accession # Q3C2E2
His
C-term
蛋白长度

Full Length

同用名
Ms4a1; Cd20; Ly-44; Ms4a2; B-lymphocyte antigen CD20; B-cell differentiation antigen Ly-44; Lymphocyte antigen 44; CD antigen
预测分子量
35.2 kDa
分子量

Approximately 25 kDa & 40 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

糖基化修饰
Yes
纯度

Greater than 80% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH7.5 with trehalose as protectant.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD20/MS4A1 Protein, Dog (HEK293, His, Nanodisc)
目录号:
HY-P704448
需求量: