CD200 蛋白, Mouse (HEK293, His)

CD200 protein functions as a costimulator of T-cell proliferation and is implicated in the potential regulation of myeloid cell activity across various tissues. Through their N-terminal Ig-like domains, CD200 interacts with CD200R1, establishing a molecular interaction that likely contributes to the modulation of immune responses and cellular activities. CD200 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD200 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD200 Protein, Mouse (HEK293, His) is 232 a.a., with molecular weight of ~24 kDa.

CD200 蛋白在免疫调节中发挥着关键作用，作为促进 T 细胞增殖的共刺激分子。此外，正如基于相似性的推论所表明的，CD200 参与了跨不同组织的骨髓细胞活性的潜在调节。CD200 与其受体 CD200R1 之间的相互作用是通过它们各自的 N 端 Ig 样结构域促进的。这种相互作用可能有助于参与免疫反应和骨髓细胞功能的调节过程。CD200 与 CD200R1 的结合强调了其在介导免疫细胞通讯和稳态方面的重要性，强调了其作为免疫调节关键参与者的潜力。

Measured by its binding ability in a functional ELISA . Immobilized recombinant mouse CD200 at 1 μg/mL (100 μl/well) can bind mouse CD200R1/Fc with a linear range of 1.5-200 ng/mL.

Mouse

HEK293

C-His

O54901 (M1-G232)

17470  [NCBI]

MGSLVFRRPFCHLSTYSLIWGMAAVALSTAQVEVVTQDERKALHTTASLRCSLKTSQEPLIVTWQKKKAVSPENMVTYSKTHGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMCLFNTFGSQKVSGTACLTLYVQPIVHLHYNYFEDHLNITCSATARPAPAISWKGTGTGIENSTESHFHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKG

Approximately 24 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.