1. 重组蛋白
  2. CD Antigens Complement System
  3. B Cell CD Proteins Epithelial cell CD Proteins Complement Receptor
  4. CD21/CR2 Complement Receptor 2
  5. CD21 蛋白, Mouse (HEK293, His)

CD21 蛋白, Mouse (HEK293, His)

目录号: HY-P77602
产品使用指南

CD21蛋白作为补体C3d和HNRNPU的受体,在B淋巴细胞激活中发挥着至关重要的作用。它与 CD19、CR2/CD21、CD81 和 IFITM1/CD225 形成复合物,有助于免疫反应。CD21 蛋白, Mouse (HEK293, His) 是重组的 CD21 蛋白,由 HEK293 表达,带有 C-His 标签。CD21 蛋白, Mouse (HEK293, His) 全长 952 个氨基酸,分子量为 130-150 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

CD21 protein, as a receptor for complement C3d and HNRNPU, plays a crucial role in B lymphocyte activation. It forms complexes with CD19, CR2/CD21, CD81 and IFITM1/CD225 and contributes to immune responses. CD21 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD21 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD21 Protein, Mouse (HEK293, His) is 952 a.a., with molecular weight of 130-150 kDa.

研究背景

CD21 蛋白作为补体 C3d 和 HNRNPU 的受体,是 B 淋巴细胞激活不可或缺的一部分。通过与 C3 和 CD19 的相互作用,CD21 参与免疫反应,并形成成熟 B 细胞膜上包含 CD19、CR2/CD21、CD81 和 IFITM1/CD225 的复合物的一部分。复杂的相互作用网络,特别是通过 Sushi 结构域 1 和 2,强调了 CD21 在调节免疫信号传导中的作用。此外,CD21 与 FCER2 结合,特别是通过 C 末端结合,强调了它参与各种细胞过程,并强调了它在 B 细胞激活和免疫调节中的重要性。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

P19070 (I12-W963)

基因 ID

12902  [NCBI]

蛋白结构
N-term
CD21 (I12-W963)
Accession # P19070
His
C-term
同用名
EBV receptor; CD21; C3DR; CR2; C3DRSLEB9; CVID7; SLEB9
分子量

130-150 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD21 Protein, Mouse (HEK293, His)
目录号:
HY-P77602
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