1. 重组蛋白
  2. CD Antigens
  3. B Cell CD Proteins Stem Cell CD Proteins Epithelial cell CD Proteins Cell Adhesion-related CD Proteins
  4. CD24/Heat-stable Antigen
  5. CD24 蛋白, Mouse (27a.a, HEK293, mFc)

CD24 蛋白, Mouse (27a.a, HEK293, mFc)

目录号: HY-P78255
产品使用指南

CD24 蛋白可以协调各种细胞类型的细胞分化,特别是在早期胸腺细胞发育中。其信号传导的激活涉及凝集素样配体与 CD24 碳水化合物的结合,触发 GPI 锚释放第二信使。CD24 蛋白, Mouse (27a.a, HEK293, mFc) 是重组的 CD24 蛋白,由 HEK293 表达,带有 C-mFc 标签。CD24 蛋白, Mouse (27a.a, HEK293, mFc) 全长 27 个氨基酸,分子量为 58-62 kDa。

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描述

The CD24 protein may coordinate cellular differentiation of various cell types, particularly in early thymocyte development. Activation of its signaling involves binding of a lectin-like ligand to the CD24 carbohydrate, triggering the release of second messengers from GPI anchors. CD24 Protein, Mouse (27a.a, HEK293, mFc) is the recombinant mouse-derived CD24 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CD24 Protein, Mouse (27a.a, HEK293, mFc) is 27 a.a., with molecular weight of 58-62 kDa.

研究背景

CD24 蛋白被认为在各种细胞类型的细胞分化过程中发挥着关键作用,在早期胸腺细胞发育中具有特定的意义。其信号传导潜力被认为是由凝集素样配体与 CD24 碳水化合物的结合触发的,并通过 GPI 锚衍生的第二信使的释放进行转导。此外,CD24 还参与调节 B 细胞激活反应,表明其对免疫过程的调节影响。与 SIGLEC10 结合,CD24 可能参与选择性抑制对危险相关分子模式 (DAMP)(例如 HMGB1、HSP70 和 HSP90)的免疫反应。这种 CD24:SIGLEC10 复合物被认为可以抑制 HMGB1 介导的组织损伤免疫反应,表明 CD24 在免疫调节和自身免疫控制中的作用。CD24 的多方面功能强调了其在多种细胞和免疫过程中发挥关键作用的潜力。

种属

Mouse

表达系统

HEK293

标签

C-mFc

蛋白编号

P24807 (Q27-G53)

基因 ID

12484  [NCBI]

蛋白结构
N-term
CD24 (Q27-G53)
Accession # P24807
mFc
C-term
同用名
CD 24; CD24 molecule; CD24A; FLJ22950; FLJ43543; MGC75043
分子量

58-62 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD24 Protein, Mouse (27a.a, HEK293, mFc)
目录号:
HY-P78255
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