2. 重组蛋白
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins
  5. TNF Receptor Superfamily CD27
  6. CD27/TNFRSF7 蛋白, Rat (HEK293, Fc)

CD27/TNFRSF7 蛋白, Rat (HEK293, Fc)

目录号: HY-P75427
产品使用指南

CD27/TNFRSF7 蛋白预计具有肽链内切酶抑制剂活性、对乙醇有反应并且是膜定位的。其人类 CD27 的直系同源物与淋巴细胞增殖综合征 2 相关，强调免疫系统调节。CD27/TNFRSF7 蛋白, Rat (HEK293, Fc) 是重组的 CD27/TNFRSF7 蛋白，由 HEK293 表达，带有 C-hFc 标签。CD27/TNFRSF7 蛋白, Rat (HEK293, Fc) 全长 183 个氨基酸，分子量约为 ~45 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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描述

The CD27/TNFRSF7 protein is predicted to have endopeptidase inhibitor activity, be ethanol responsive, and be membrane localized. Its ortholog of human CD27 has been implicated in lymphoproliferative syndrome 2, emphasizing immune system regulation. CD27/TNFRSF7 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD27/TNFRSF7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD27/TNFRSF7 Protein, Rat (HEK293, Fc) is 183 a.a., with molecular weight of ~45 kDa.
研究背景

CD27/TNFRSF7 蛋白预计会表现出参与细胞凋亡过程的半胱氨酸型内肽酶抑制剂活性，并参与细胞对乙醇的反应。该蛋白质主要位于膜中。该基因的人类直系同源物与淋巴细胞增殖综合征 2 相关，凸显了其在免疫系统调节中的作用。作为人类 CD27（CD27 分子）的直系同源对应物，CD27/TNFRSF7 表现出偏向表达，在胸腺 (RPKM 187.5)、脾脏 (RPKM 34.1) 和一种其他组织中观察到显着水平。这种表达模式强调了它对免疫功能的潜在参与，特别是在淋巴组织中，并表明它在响应乙醇等特定刺激而调节细胞凋亡过程中具有特殊作用。
种属

Rat
表达系统

HEK293
标签

C-hFc
蛋白编号

NP_001019506 (M1-R183)
基因 ID

500318  [NCBI]
蛋白结构
N-term
CD27 (M1-R183)
Accession # NP_001019506
hFc
C-term
同用名
CD27 antigen; T cell activation antigen CD27; T14; TNFRSF7
分子量

Approximately 45 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD27/TNFRSF7 Protein, Rat (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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