CD38 蛋白, Rabbit (HEK293, His)

CD38 protein performs diverse functions, synthesizing cyclic ADP-ribose (cADPR) for glucose-induced insulin secretion. It produces nicotinate-adenine dinucleotide phosphate (NAADP+), mobilizing calcium ions through 2'-phospho-cADPR and nicotinic acid, along with NADP+ and nicotinic acid. Additionally, CD38 acts as a cADPR hydrolase. CD38 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived CD38 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD38 Protein, Rabbit (HEK293, His) is 256 a.a., with molecular weight of 33-49 kDa.

CD38 蛋白具有多种功能，包括合成环状 ADP-核糖 (cADPR)，这是参与葡萄糖诱导的胰岛素分泌的第二信使。它还负责使用 2'-磷酸-cADPR 和烟酸以及 NADP(+) 和烟酸产生烟酸腺嘌呤二核苷酸磷酸盐 NAADP(+)，从而动员钙离子。此外，CD38 表现出 cADPR 水解酶活性。

Immobilized Human CD38 at 1 μg/mL (100 μL/well) can bind Anti-CD38 Antibody. The ED₅₀ for this effect is 20.91 ng/mL.

Rabbit

HEK293

C-His

Q9MZ03 (L43-M298)

100009409  [NCBI]

LTWRQSSMGATDHVSAIVLGRCLTYTRNMHPELRNQDCKKILNTFTSAFVSKDPCNITKEDYQPLIDLVTQTVPCNKTLFWSRSKELAHQYSGIQKEMFTLEDTLLGYIADNLVWCGDPRTSEVKEEFCPYRNENCSSTATSVFWTVVSQKFAESACGTVYVMLNGSRTTAFSKASTFGSVEVFNLHPDRVHTLHAWVMHDIGGVERDSCLGSSIKELKSIVNQRNISFFCQDDYRPARFVQCVRHPEHPSCSVLM

33-49 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, PH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.