1. 重组蛋白
  2. CD Antigens
  3. T Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins
  4. CD39
  5. CD39 蛋白, Human (Active, R138A, M139A, E142K, HEK293, His)

CD39 蛋白, Human (Active, R138A, M139A, E142K, HEK293, His)

目录号: HY-P704469
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CD39蛋白是神经系统中的重要调节因子,通过水解ATP和其他核苷酸来协调嘌呤能神经传递。其酶活性可将血小板活化的ADP水解成AMP,从而有效阻止血小板聚集。CD39 蛋白, Human (Active, R138A, M139A, E142K, HEK293, His) 是重组的 CD39 蛋白,由 HEK293 表达,带有 C-His 标签。

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描述

The CD39 protein is an important regulator in the nervous system, coordinating purinergic neurotransmission by hydrolyzing ATP and other nucleotides. Its enzymatic ability can hydrolyze platelet-activated ADP into AMP, thereby effectively preventing platelet aggregation. CD39 Protein, Human (Active, R138A, M139A, E142K, HEK293, His) is the recombinant human-derived CD39 protein, expressed by HEK293, with C-His labeled tag.

研究背景

在神经系统中,CD39 蛋白通过水解 ATP 和其他核苷酸,充当嘌呤能神经传递的关键调节剂。其酶活性延伸至预防血小板聚集,因为它能有效地将血小板活化的 ADP 水解为 AMP。值得注意的是,CD39 在水解 ATP 和 ADP 方面表现出同等的能力,强调了其在调节嘌呤能信号通路以及促进神经传递和血小板功能的复杂调节方面的多功能作用。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P49961 (T38-V478)

基因 ID

23621

蛋白结构
N-term
CD39 (T38-V478, R138A, M139A, E142K)
Accession # P49961
His
C-term
同用名
Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-apyrase; CD39; Entpd1
预测分子量
52.2 kDa
分子量

Approximately 60-68 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

糖基化修饰
Yes
纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CD39 Protein, Human (Active, R138A, M139A, E142K, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD39 Protein, Human (Active, R138A, M139A, E142K, HEK293, His)
目录号:
HY-P704469
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