CD39 蛋白, Mouse (HEK293, His)

The CD39 protein, expressed in the nervous system, regulates purinergic neurotransmission by hydrolyzing ATP and other nucleotides. It also prevents platelet aggregation by hydrolyzing platelet-activating ADP to AMP. CD39's proficiency in hydrolyzing both ATP and ADP underscores its versatile role in modulating purinergic signaling, influencing neurotransmission and platelet function. Its dual enzymatic activity maintains the delicate balance of purinergic signaling in the nervous system and hemostasis. CD39 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD39 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD39 Protein, Mouse (HEK293, His) is 441 a.a., with molecular weight of 60-90 kDa.

CD39 蛋白在神经系统中显着表达，通过水解 ATP 和其他核苷酸，在嘌呤能神经传递的调节中发挥着至关重要的作用。此外，CD39 通过将血小板活化 ADP 水解为 AMP 来防止血小板聚集。值得注意的是，CD39 在水解 ATP 和 ADP 方面表现出同等的能力，强调了其在调节嘌呤能信号通路和促进影响神经传递和血小板功能的调节机制方面的多功能性。 CD39 的双重酶活性凸显了其在维持神经系统内嘌呤能信号传导的微妙平衡和更广泛的止血方面的重要性。

Mouse

HEK293

C-6*His

P55772(T38-I478)

12495  [NCBI]

TQNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQQLEECQVKGPGISKYAQKTDEIGAYLAECMELSTELIPTSKHHQTPVYLGATAGMRLLRMESEQSADEVLAAVSTSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLSLISDSQKQETFGALDLGGASTQITFVPQNSTIESPENSLQFRLYGEDYTVYTHSFLCYGKDQALWQKLAKDIQVSSGGVLKDPCFNPGYEKVVNVSELYGTPCTKRFEKKLPFDQFRIQGTGDYEQCHQSILELFNNSHCPYSQCAFNGVFLPPLHGSFGAFSAFYFVMDFFKKVAKNSVISQEKMTEITKNFCSKSWEETKTSYPSVKEKYLSEYCFSGAYILSLLQGYNFTDSSWEQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYI

60-90 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl,500 mM NaCl, 10% Glycerol, pH 7.4.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.