CD39L1/ENTPD2 蛋白, Human (HEK293, His)

CD39L1/ENTPD2 protein, expressed in the nervous system, efficiently hydrolyzes ATP and various nucleotides, while showing limited hydrolysis of ADP. Its substrate specificity hierarchy highlights its regulatory role in purinergic signaling and selective nucleotide hydrolysis, contributing to precise control of neurotransmission. CD39L1/ENTPD2 Protein, Human (HEK293, His) is the recombinant human-derived CD39L1/ENTPD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD39L1/ENTPD2 Protein, Human (HEK293, His) is 432 a.a., with molecular weight of ~60 kDa.

CD39L1/ENTPD2蛋白主要在神经系统中表达，通过有效水解ATP和各种核苷酸，在嘌呤能神经传递的调节中发挥关键作用。值得注意的是，CD39L1/ENTPD2 仅表现出 ADP 的边缘水解，表明其底物特异性将其与更广泛的核苷酸水解区分开来。不同底物的酶活性顺序揭示了优先等级，其中 ATP 被最有效地水解，其次是 GTP、CTP、ITP 和 UTP，而 ADP 和 UDP 显示出相当低的水解效率。这种微妙的底物特异性强调了 CD39L1/ENTPD2 在调节神经系统内嘌呤能信号通路中的复杂调节作用，强调了它通过选择性核苷酸水解对神经传递的精细控制的贡献。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

Q9Y5L3 (T29-D460)

954  [NCBI]

TRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTD

Approximately 60 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 10% Glycerol, pH 7.4.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.