1. 重组蛋白
  2. CD Antigens
  3. T Cell CD Proteins B Cell CD Proteins Dendritic Cell CD Proteins Cell Adhesion-related CD Proteins
  4. CD5
  5. CD5 蛋白, Human (HEK293, His)

CD5 蛋白, Human (HEK293, His)

目录号: HY-P72920
COA 产品使用指南

CD5 蛋白是调节 T 细胞增殖的潜在受体。它与 CD72/LYB-2 和 PTPN6/SHP-1 的相互作用表明在细胞过程中发挥多方面的作用,充当 T 细胞反应的关键介质。CD5 蛋白, Human (HEK293, His) 是重组的 CD5 蛋白,由 HEK293 表达,带有 C-His 标签。CD5 蛋白, Human (HEK293, His) 全长 348 个氨基酸,分子量约为 ~48.9 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
Free Sample   Apply now  
5 μg ¥350 In-stock
10 μg ¥500 In-stock
50 μg ¥1400 In-stock
100 μg ¥2400 In-stock
500 μg ¥7600 In-stock
1 mg ¥13600 In-stock
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The CD5 protein is a potential receptor that regulates T cell proliferation. Its interactions with CD72/LYB-2 and PTPN6/SHP-1 indicate multifaceted roles in cellular processes, serving as key mediators of T cell responses. CD5 Protein, Human (HEK293, His) is the recombinant human-derived CD5 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD5 Protein, Human (HEK293, His) is 348 a.a., with molecular weight of ~48.9 kDa.

研究背景

CD5 蛋白本身是一种参与 T 细胞增殖调节的潜在受体。它与 CD72/LYB-2 和 PTPN6/SHP-1 的相互作用表明其在调节细胞过程中具有多方面的作用。作为受体,这种蛋白质可能在协调 T 细胞反应、介导与其他细胞成分的重要相互作用中发挥关键作用。与 CD72/LYB-2 和 PTPN6/SHP-1 的结合强调了其参与复杂的信号传导途径,暗示其在控制 T 细胞行为的调控网络中的重要性。进一步探索 CD5 蛋白的功能可以为 T 细胞增殖和免疫调节的分子机制提供有价值的见解。

生物活性

Immobilized Human CD5 at 2 μg/mL (100 μL/well) can bind Anti-CD5 Antibody. The ED50 for this effect is 19.66 ng/mL.

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P06127 (R25-P372)

基因 ID

921  [NCBI]

蛋白结构
N-term
CD5 (R25-P372)
Accession # P06127
His
C-term
中文名
重组人CD5蛋白
同用名
T-cell surface glycoprotein CD5; Ly-1; Lyt-1; CD5; Leu-1
氨基酸序列

RLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNP

分子量

Approximately 48.9 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD5 Protein, Human (HEK293, His)
目录号:
HY-P72920
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