CD64 蛋白, Rat (HEK293, His)

CD64 Protein, with leukotriene receptor binding, crucially regulates processes like phagocytosis and pain perception, responding to epinephrine. Located in membrane rafts, CD64, encoded by FCGR1A, shows biased expression, especially in Spleen (RPKM 177.3) and Lung (RPKM 93.7). This emphasizes its importance in immune responses and sensory functions across diverse physiological contexts. CD64 Protein, Rat (HEK293, His) is the recombinant rat-derived CD64 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD64 Protein, Rat (HEK293, His) is 269 a.a., with molecular weight of 40-42 kDa.

CD64 蛋白以其白三烯受体结合活性为特征，在多种生物过程中发挥着至关重要的作用，包括吞噬作用的正向调节、疼痛的感觉以及对肾上腺素的反应。由 FCGR1A 基因编码的 CD64 位于膜筏中，表现出偏向的表达模式，在脾 (RPKM 177.3)、肺 (RPKM 93.7) 和其他九个组织中具有显着水平。这强调了它在不同生理环境下的免疫反应和感觉功能中的重要性。

Measured by its binding ability in a functional ELISA. Immobilized Rat CD64-his at 10 μg/mL (100 μL/well) can bind biotinylated human IgG1. The ED₅₀ for this effect is 0.0754 μg/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized Rat CD64-his at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1,The ED₅₀ for this effect is 0.0754 μg/mL.

Rat

HEK293

C-His

NP_001094306 (V17-P285)

295279  [NCBI]

VVNATKAVVTLQPPWLSIFQEENVTLLCEGPHLGDSSTKWFINSTAIQISTPTYSILKASFKDSGEYKCQTGLSMPSDPVQLEIYRDWLLLQTSHRVLTEGEPLALRCHPWQNKKVYNVAFYRNGESLDFSQGSEVTILKTNLSHSGIYHCSAMGKKLFKSAGVSVTVKELFATPVLRVSLSSPFPEGSLVILNCETRLFLQSPGLRLYFSFYVGSKILEDRSTSSEYHIPRAEREDDGSYWCEVATEDGRVLKRSTKLELFGPQSSDP

40-42 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.