CD68 蛋白, Mouse (sf9, His)

The CD68 protein plays a crucial role in the phagocytic activity of tissue macrophages, affecting lysosomal metabolism and interactions with cells and pathogens. It binds to specific lectins or selectins and guides macrophages to migrate to specific sites. CD68 Protein, Mouse (sf9, His) is the recombinant mouse-derived CD68 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of CD68 Protein, Mouse (sf9, His) is 291 a.a., with molecular weight of ~30.2 kDa.

CD68 蛋白可能在组织巨噬细胞的吞噬活性中发挥关键作用，影响细胞内溶酶体代谢和涉及细胞-细胞和细胞-病原体接触的细胞外相互作用。它表现出与组织和器官特异性凝集素或选择素的结合能力，促进不同的巨噬细胞亚群归巢到特定的解剖部位。CD68从内体和溶酶体到质膜的快速再循环表明了一种动态机制，使巨噬细胞能够导航和穿越带有选择素的底物或与其他细胞相互作用。CD68 的这种多方面功能强调了它在不同组织微环境中的免疫反应和细胞相互作用的复杂过程中的重要性。

Mouse

Sf9 insect cells

C-His

P31996 (M1-S291)

12514  [NCBI]

Approximately 30.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0, 10% Glycerol. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.