1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Stem Cell CD Proteins Epithelial cell CD Proteins
  4. CD318/CDCP1
  5. CDCP1 蛋白, Mouse (643a.a, HEK293, His)

CDCP1 蛋白, Mouse (643a.a, HEK293, His)

目录号: HY-P78268
COA 产品使用指南

CDCP1 蛋白与细胞粘附和基质缔合有关,表明其在重要的细胞相互作用中发挥作用。其磷酸化表明在调节锚定、迁移、增殖或分化方面具有动态功能。CDCP1 蛋白, Mouse (643a.a, HEK293, His) 是重组的 CDCP1 蛋白,由 HEK293 表达,带有 C-His 标签。CDCP1 蛋白, Mouse (643a.a, HEK293, His) 全长 643 个氨基酸,分子量为 90-110 kDa。

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规格 价格 是否有货 数量
20 μg ¥2000 In-stock
50 μg ¥3800 In-stock
100 μg ¥6080 询价
> 100 μg   询价  

* Please select Quantity before adding items.

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描述

The CDCP1 protein has been implicated in cell adhesion and matrix association, suggesting a role in important cellular interactions. Its phosphorylation suggests a dynamic function in regulating anchorage, migration, proliferation, or differentiation. CDCP1 Protein, Mouse (643a.a, HEK293, His) is the recombinant mouse-derived CDCP1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CDCP1 Protein, Mouse (643a.a, HEK293, His) is 643 a.a., with molecular weight of 90-110 kDa.

研究背景

CDCP1 蛋白似乎参与细胞粘附和细胞基质缔合,表明其在介导对细胞过程至关重要的相互作用中发挥作用。正如其磷酸化所示,它可能参与锚定与迁移或增殖与分化的调节,这意味着在调节细胞行为中发挥着动态作用。此外,CDCP1可以作为白血病诊断和未成熟造血干细胞亚群的新标记物,提供潜在的诊断和治疗见解。作为与肿瘤进展和转移有关的四跨膜蛋白网络的成员,CDCP1 与关键分子相互作用,包括 CDH2/N-钙粘蛋白、CDH3/P-钙粘蛋白、SDC1/syndecan-1、SDC4/syndecan-4、丝氨酸蛋白酶 ST14/MT -SP1、SRC 和 PRKCG/蛋白激酶 C γ。其相互作用的多样性强调了其对细胞过程的潜在影响,并表明其在正常和病理条件下具有多方面的作用。进一步探索CDCP1的功能和调节机制可以更深入地了解其对细胞动力学的贡献及其作为治疗靶点的潜力。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

Q5U462 (R25-A667)

基因 ID

109332  [NCBI]

蛋白结构
N-term
CDCP1 (R25-A667)
Accession # Q5U462
His
C-term
同用名
CDCP1; CD318; SIMA135; TRASK; UNQ2486; PRO5773
分子量

90-110 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CDCP1 Protein, Mouse (643a.a, HEK293, His)
目录号:
HY-P78268
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