1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. CDNF/MANF family
  5. CDNF
  6. CDNF 蛋白, Human (HEK293, Fc)

CDNF 蛋白, Human (HEK293, Fc)

目录号: HY-P76248
产品使用指南

CDNF(大脑多巴胺神经营养因子)作为重要的营养因子,为多巴胺神经元提供独特的支持。其保护作用对于防止6-羟基多巴胺(6-OHDA)诱导的多巴胺能神经元变性有明显作用。CDNF 蛋白, Human (HEK293, Fc) 是重组的 CDNF 蛋白,由 HEK293 表达,带有 C-hFc 标签。CDNF 蛋白, Human (HEK293, Fc) 全长 187 个氨基酸,分子量约为 ~45.2 KDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

CDNF (cerebral dopamine neurotrophic factor) functions as an important trophic factor, providing unique support to dopamine neurons. Its protective effect has a clear role in preventing 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. CDNF Protein, Human (HEK293, Fc) is the recombinant human-derived CDNF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CDNF Protein, Human (HEK293, Fc) is 187 a.a., with molecular weight of ~45.2 KDa.

研究背景

CDNF(大脑多巴胺神经营养因子)作为一种重要的营养因子而出现,在支持多巴胺神经元方面具有独特的作用。其保护能力延伸至防止 6-羟基多巴胺 (6-OHDA) 诱导的多巴胺能神经元变性。值得注意的是,当在 6-OHDA 损伤后施用时,CDNF 表现出恢复多巴胺能功能并有效阻止黑质内神经元变性的显着能力,强调了其在减轻神经退行性过程中的治疗潜力。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q49AH0 (M1-L187)

基因 ID
蛋白结构
N-term
CDNF (M1-L187)
Accession # Q49AH0
hFc
C-term
同用名
Cerebral dopamine neurotrophic factor; ARMET-like protein 1; ARMETL1
分子量

Approximately 45.2 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CDNF Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
CDNF Protein, Human (HEK293, Fc)
目录号:
HY-P76248
需求量: