CECR1 蛋白, Human (sf9, His)

CECR1, an adenosine deaminase, degrades extracellular adenosine, a pivotal signaling molecule, with activity dependent on elevated adenosine levels. It binds cell surfaces through proteoglycans, hinting at roles in cell proliferation and differentiation beyond its enzyme function. This dual functionality highlights its potential significance in cellular regulatory processes. CECR1 Protein, Human (sf9, His) is the recombinant human-derived CECR1 protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of CECR1 Protein, Human (sf9, His) is 511 a.a., with molecular weight of ~58 KDa.

CECR1 是一种腺苷脱氨酶，参与细胞外腺苷的降解，而细胞外腺苷是控制多种细胞反应的关键信号分子。其酶活性取决于腺苷水平的升高。CECR1表现出通过蛋白聚糖与细胞表面结合的倾向，这表明其在调节细胞增殖和分化方面的潜在作用超出了其典型的酶功能。这种双重功能强调了其在复杂的细胞调节过程中的潜在重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

Sf9 insect cells

C-His

Q9NZK5 (M1-K511)

51816  [NCBI]

Approximately 58 kDa.

Greater than 90% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 10% Glycerol, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.