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  3. CERS6 蛋白, Human (HEK293, His, Strep)

CERS6 蛋白, Human (HEK293, His, Strep)

目录号: HY-P703403
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CERS6 蛋白, Human (HEK293, His, Strep) 是重组的 CERS6 蛋白,由 HEK293 表达,带有 Strep, His 标签。CERS6 蛋白, Human (HEK293, His, Strep)

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规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

CERS6 Protein, Human (HEK293, His, Strep) is the recombinant human-derived CERS6, expressed by HEK293 , with Strep, His labeled tag. ,

研究背景

CERS6 是一种 ceramide synthase,能够催化将酰基链从 acyl-CoA 转移到 sphingoid base 的过程,对 palmitoyl-CoA (hexadecanoyl-CoA;C16:0-CoA) 具有高度选择性。它还可以使用其他酰基供体,但效率较低 (By similarity)。在 de novo synthesis 和 salvage pathways 中,CERS6 通过 N-acylate sphinganine 和 sphingosine bases 分别生成 dihydroceramides 和 ceramides。CERS6 生成的 ceramides 参与炎症反应 (By similarity),并调节代谢和肝脏脂质积累 (By similarity)。在高脂饮食条件下,CERS6 生成的 palmitoyl- (C16:0-) ceramides 会与线粒体分裂因子 MFF 结合,促进线粒体断裂,从而促进肥胖的发生 (By similarity)。

种属

Human

表达系统

HEK293

标签

Strep;His

蛋白编号

Q6ZMG9-1 (M1-D384end)

基因 ID

253782

蛋白长度

Full Length of Isoform-1

中文名
CERS6 蛋白
同用名
LASS6
预测分子量
49 kDa
糖基化修饰
Yes
内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CERS6 Protein, Human (HEK293, His, Strep) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CERS6 Protein, Human (HEK293, His, Strep)
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