1. 重组蛋白
  2. Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. CLL-1
  6. CLEC12A/MICL 蛋白, Human (HEK293, Fc)

CLEC12A/MICL 蛋白, Human (HEK293, Fc)

目录号: HY-P77631
COA 产品使用指南

CLEC12A/MICL 是一种细胞表面受体,已知可调节信号级联并促进目标 MAP 激酶的酪氨酸磷酸化。它与 PTPN6 和 PTPN11 相互作用,表明它参与复杂的细胞信号传导过程。CLEC12A/MICL 蛋白, Human (HEK293, Fc) 是重组的 CLEC12A/MICL 蛋白,由 HEK293 表达,带有 N-hFc 标签。CLEC12A/MICL 蛋白, Human (HEK293, Fc) 全长 201 个氨基酸,分子量为 68-73 kDa。

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规格 价格 是否有货 数量
20 μg ¥1500 In-stock
50 μg ¥3300 In-stock
100 μg ¥5600 询价
> 100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

CLEC12A/MICL is a cell surface receptor known to regulate signaling cascades and facilitate the tyrosine phosphorylation of target MAP kinases. It interacts with PTPN6 and PTPN11, indicating its involvement in intricate cellular signaling processes. CLEC12A/MICL Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CLEC12A/MICL Protein, Human (HEK293, Fc) is 201 a.a., with molecular weight of 68-73 kDa.

研究背景

CLEC12A/MICL 是一种细胞表面受体,已知可调节信号级联并促进目标 MAP 激酶的酪氨酸磷酸化。它与 PTPN6 和 PTPN11 相互作用,表明它参与复杂的细胞信号传导过程。

生物活性

Immobilized Human CLEC12A, hFc Tag at 0.5 μg/mL (100μL/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC12A Antibody, hFc Tag with the EC50 of 34.8-37.8 ng/mL determined by ELISA.

种属

Human

表达系统

HEK293

标签

N-hFc

蛋白编号

Q5QGZ9-2 (H65-A265)

基因 ID
蛋白结构
N-term
hFc
CLEC12A (H65-A265)
Accession # Q5QGZ9-2
C-term
同用名
MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2
分子量

68-73 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

CLEC12A/MICL Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CLEC12A/MICL Protein, Human (HEK293, Fc)
目录号:
HY-P77631
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