2. 重组蛋白
  3. Receptor Proteins
  4. Pattern Recognition Receptors
  5. C-type Lectin Receptors
  6. Macrophage-inducible C-type Lectin/CLEC4E
  7. CLEC4E 蛋白, Rhesus Macaque (HEK293, Fc)

CLEC4E 蛋白, Rhesus Macaque (HEK293, Fc)

目录号: HY-P77336
COA 产品使用指南

CLEC4E 蛋白是一种钙依赖性凝集素，具有甘露糖结合特异性，并诱导 Birbeck 颗粒 (BGs) 的形成。CLEC4E 蛋白是膜叠加和拉链的有效调节剂，并与硫酸盐和甘露糖基化聚糖、硫酸角蛋白 (KS) 和 β -葡聚糖结合。CLEC4E 蛋白, Rhesus Macaque (HEK293, Fc) 是重组的 CLEC4E 蛋白，由 HEK293 表达，带有 N-hFc 标签。CLEC4E 蛋白, Rhesus Macaque (HEK293, Fc) 全长 179 个氨基酸，分子量约为 ~49.1 KDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
50 μg ￥3200 In-stock
100 μg ￥5100 In-stock
> 100 μg   询价  

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描述

CLEC4E Protein is a calcium-dependent lectin displaying mannose-binding specificity, and induces the formation of Birbeck granules (BGs). CLEC4E Protein is a potent regulator of membrane superimposition and zippering, and binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. CLEC4E Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CLEC4E protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CLEC4E Protein, Rhesus Macaque (HEK293, Fc) is 179 a.a., with molecular weight of ~49.1 KDa.
研究背景

CLEC4E Protein 促进抗原的摄取，并参与抗原递送到T细胞的路径或加工。C-type lectin domain family 4 member E 是念珠菌、酵母菌和马拉色菌原代朗格汉斯细胞上的主要受体。C-type lectin domain family 4 member E 对人类免疫缺陷病毒1 (HIV-1) 感染的保护作用。
种属

Rhesus Macaque
表达系统

HEK293
标签

N-hFc
蛋白编号

XP_001118423 (R41-I219)
基因 ID

722250  [NCBI]
蛋白结构
N-term
hFc
CLEC4E (R41-I219)
Accession # XP_001118423
C-term
同用名
C-Type Lectin Domain Family 4 Member E; CLECSF9; MINCLE
分子量

Approximately 49.1 kDa.
纯度

Greater than 85% as determined by reducing SDS-PAGE.
性状

溶液
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

CLEC4E Protein, Rhesus Macaque (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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