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  3. ClpC1 NTD 蛋白, Mycobacterium tuberculosis

ClpC1 NTD 蛋白, Mycobacterium tuberculosis

目录号: HY-P701867
产品使用指南

ClpC1 NTD 蛋白是 Clp 蛋白酶的 ATP 依赖性特异性成分,可将蛋白酶引导至特定底物,并表现出独立于 ClpP 的伴侣功能。在 ClpP2 存在的情况下,它在底物(例如抗 Sigma-E 因子 RseA)的定向降解中发挥着至关重要的作用。ClpC1 NTD 蛋白, Mycobacterium tuberculosis 是重组的 ClpC1 NTD 蛋白,由 E. coli 表达,不带标签。ClpC1 NTD 蛋白, Mycobacterium tuberculosis 全长 145 个氨基酸。

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描述

ClpC1 NTD Protein, the ATP-dependent specificity component of the Clp protease, directs the protease to specific substrates and exhibits chaperone functions independently of ClpP. It plays a crucial role in the targeted degradation of substrates, such as the anti-sigma-E factor RseA, in the presence of ClpP2. ClpC1 NTD Protein, Mycobacterium tuberculosis is the recombinant ClpC1 NTD protein, expressed by E. coli , with tag free. The total length of ClpC1 NTD Protein, Mycobacterium tuberculosis is 145 a.a., .

研究背景

作为 Clp 蛋白酶的 ATP 依赖性特异性成分,ClpC1 NTD 蛋白在引导蛋白酶针对特定底物方面发挥着关键作用。除了其在底物特异性中的作用外,即使在 ClpP 不存在的情况下,ClpC1 NTD 也表现出伴侣功能。值得注意的是,当 ClpP2 存在时,该蛋白参与抗 Sigma-E 因子 RseA 的降解,强调了其在靶向蛋白降解过程中的重要性。

种属

Others

表达系统

E. coli

标签

Tag Free

蛋白编号

P9WPC9 (M1-Y145)

基因 ID

45427583

蛋白结构
N-term
ClpC1 NTD (M1-Y145)
Accession # P9WPC9
C-term
同用名
clpC1; ATP-dependent Clp protease ATP-binding subunit ClpC1
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

ClpC1 NTD Protein, Mycobacterium tuberculosis 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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