1. 重组蛋白
  2. Receptor Proteins
  3. G-Protein-Coupled Receptors (GPCRs)
  4. Cannabinoid Receptor
  5. CNR2 蛋白, Human (Cell-Free, His)

CNR2 蛋白, Human (Cell-Free, His)

目录号: HY-P702255
COA 产品使用指南 技术支持

CNR2 蛋白是一种异源三聚体 G 蛋白偶联受体,可显着抑制腺苷酸环化酶,介导炎症反应、伤害性传递和骨稳态中的功能。它对细胞信号传导的调节强调了其在生理过程中的重要性,将 CNR2 蛋白定位为炎症、感觉机制和骨骼平衡的关键调节剂。CNR2 蛋白, Human (Cell-Free, His) 是重组的 CNR2 蛋白,由 E. coli Cell-free 表达,带有 N-10*His 标签。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
20 μg ¥4600 In-stock
50 μg ¥8000 询价
100 μg   询价  

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描述

CNR2 Protein, a heterotrimeric G protein-coupled receptor, crucially inhibits adenylate cyclase, mediating functions in inflammatory responses, nociceptive transmission, and bone homeostasis. Its modulation of cellular signaling underscores its significance in physiological processes, positioning CNR2 Protein as a key regulator in inflammatory, sensory mechanisms, and bone equilibrium. CNR2 Protein, Human (Cell-Free, His) is the recombinant human-derived CNR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

研究背景

CNR2 蛋白 是内源性大麻素 2-花生四烯酰甘油的异三聚体 G 蛋白偶联受体,在介导腺苷酸环化酶的抑制中发挥着关键作用。其多功能功能延伸至潜在参与炎症反应、伤害性传播和骨稳态。该受体调节细胞信号传导途径的能力凸显了其在各种生理过程中的重要性,使 CNR2 蛋白在炎症和感觉机制的复杂调节中发挥关键作用,并有助于维持骨平衡。

种属

Human

表达系统

E. coli Cell-free

标签

N-10*His

蛋白编号

P34972 (M1-C360)

基因 ID

1269

蛋白结构
N-term
10*His
CNR2 (M1-C360)
Accession # P34972
C-term
蛋白长度

Full Length

中文名
CNR2 蛋白
同用名
Cannabinoid receptor 2; CX5; CB-2; CB2
氨基酸序列

MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC

分子量

42.5 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, 0.05% Brij-78, 6% trehalose, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

CNR2 Protein, Human (Cell-Free, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CNR2 Protein, Human (Cell-Free, His)
目录号:
HY-P702255
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